Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.37 |
| ▸ | PNLIP | P16233 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.31 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.31 |
| ▸ | STK39 | Q9UEW8 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27768765 | 0.91 | SLC6A4 (0.38) | HTR2ASLC6A4PDE7APNLIPKDM4E | |
| SCHEMBL27768848 | 0.83 | PDE7A (0.49) | PDE7AKDM4EMAPT | |
| SCHEMBL27948446 | 0.80 | CA12 (0.37) | HTR2AKDM4EMAPTRAD52MAPK14 | |
| SCHEMBL27768811 | 0.78 | EZH2 (0.34) | SLC6A4PDE7AKDM4EMAPTRAD52 | |
| SCHEMBL27790231 | 0.78 | MAPT (0.33) | HTR2APDE7AKDM4EMAPTRAD52 | |
| SCHEMBL27768979 | 0.76 | PDE7A (0.39) | HTR2ASLC6A4PDE7APNLIPFFAR1 | |
| SCHEMBL27790238 | 0.74 | PDE7A (0.49) | PDE7AKDM4EMAPT | |
| SCHEMBL3485002 | 0.74 | PDE7A (0.40) | HTR2ASLC6A4PDE7AKDM4EMAPT | |
| SCHEMBL27936885 | 0.72 | CA12 (0.34) | HTR2AKDM4EMAPTRAD52MAPK14 | |
| SCHEMBL3484045 | 0.72 | PDE7A (0.40) | HTR2ASLC6A4PDE7APNLIPKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101611041-A | Condensed heterocyclic compouds | TAKEDA PHARMACEUTICAL (JP) | 2009-12-23 | — | — | CN | disclosed |