Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 11/20 | 0.67 |
| ▸ | HSP90AA1 | P07900 | 10/20 | 0.67 |
| ▸ | NPC1 | O15118 | 7/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.66 |
| ▸ | PAX8 | Q06710 | 4/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.59 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.57 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2152987 | 0.89 | SLC2A1 (0.82) | RAB9AHSP90AA1NPC1L3MBTL1KMT2A | |
| SCHEMBL2153761 | 0.89 | HSP90AA1 (0.77) | RAB9AHSP90AA1NPC1L3MBTL1KMT2A | |
| SCHEMBL4044414 | 0.87 | RAB9A (0.79) | RAB9AHSP90AA1NPC1L3MBTL1KMT2A | |
| SCHEMBL2153396 | 0.83 | RAB9A (0.63) | RAB9AHSP90AA1NPC1L3MBTL1KMT2A | |
| SCHEMBL4039326 | 0.82 | RAB9A (0.78) | RAB9AHSP90AA1NPC1L3MBTL1KMT2A | |
| SCHEMBL13836264 | 0.82 | RAB9A (0.60) | RAB9AHSP90AA1NPC1L3MBTL1KMT2A | |
| SCHEMBL609720 | 0.81 | RAB9A (0.74) | RAB9AHSP90AA1NPC1L3MBTL1KMT2A | |
| SCHEMBL13498054 | 0.81 | RAB9A (1.00) | RAB9AHSP90AA1NPC1L3MBTL1KMT2A | |
| SCHEMBL16810206 | 0.79 | RAB9A (1.00) | RAB9AHSP90AA1NPC1L3MBTL1KMT2A | |
| SCHEMBL16810205 | 0.78 | RAB9A (0.83) | RAB9AHSP90AA1NPC1L3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101611009-A | Quinoline derivatives | CHRONOGEN INC (US) | 2009-12-23 | — | — | CN | claimed |
| CN-101611009-A | Quinoline derivatives | CHRONOGEN INC (US) | 2009-12-23 | — | — | CN | disclosed |