Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 7/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.45 |
| ▸ | MAPT | P10636 | 7/20 | 0.45 |
| ▸ | LMNA | P02545 | 5/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.45 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27768921 | 0.82 | KMT2A (0.47) | PDE7AMEN1KMT2AGAAPKM | |
| SCHEMBL27790312 | 0.77 | PDE7A (0.52) | PDE7AMEN1KMT2AGAAPKM | |
| SCHEMBL27768770 | 0.77 | PDE7A (0.52) | PDE7AMEN1KMT2AGAAPKM | |
| Methylamine SCHEMBL27768768 | 0.77 | PDE7A (0.52) | PDE7AMEN1KMT2AGAAPKM | |
| SCHEMBL3484209 | 0.75 | PDE7A (0.54) | PDE7AMEN1KMT2AGAAPKM | |
| SCHEMBL27768848 | 0.73 | PDE7A (0.49) | PDE7AMEN1KMT2AGAAPKM | |
| SCHEMBL27790238 | 0.73 | PDE7A (0.49) | PDE7AMEN1KMT2AGAAPKM | |
| SCHEMBL3484743 | 0.73 | PDE7A (0.54) | PDE7AMEN1KMT2AGAAPKM | |
| SCHEMBL2529627 | 0.72 | ALDH1A1 (0.67) | PDE7AMEN1KMT2AGAAPKM | |
| SCHEMBL3485062 | 0.72 | PDE7A (0.56) | PDE7AMEN1KMT2AGAAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101611041-A | Condensed heterocyclic compouds | TAKEDA PHARMACEUTICAL (JP) | 2009-12-23 | — | — | CN | disclosed |