Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.66 |
| ▸ | GAA | P10253 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 3/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.53 |
| ▸ | MTOR | P42345 | 1/20 | 0.53 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3937303 | 0.82 | EPHX2 (0.77) | EPHX2MAPTSMN1; SMN2KDM4ELMNA | |
| SCHEMBL3936624 | 0.80 | EPHX2 (1.00) | EPHX2MAPTSMN1; SMN2KDM4ELMNA | |
| SCHEMBL3943499 | 0.78 | EPHX2 (0.80) | EPHX2MAPTSMN1; SMN2LMNANPC1 | |
| SCHEMBL10986478 | 0.77 | LMNA (0.55) | GAAMAPTSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL4083187 | 0.76 | SMN1; SMN2 (0.58) | EPHX2MAPTSMN1; SMN2KDM4ELMNA | |
| SCHEMBL5594972 | 0.76 | DHODH (0.75) | GAAMAPTSMN1; SMN2KDM4ELMNA | |
| SCHEMBL30458017 | 0.76 | LMNA (0.62) | GAAKDM4ELMNAALDH1A1KMT2A | |
| SCHEMBL27786077 | 0.75 | EPHX2 (0.57) | EPHX2GAAMAPTSMN1; SMN2NPC1 | |
| SCHEMBL3944093 | 0.75 | EPHX2 (0.77) | EPHX2GAAMAPTSMN1; SMN2KDM4E | |
| SCHEMBL10992690 | 0.75 | SMN1; SMN2 (0.58) | GAAMAPTSMN1; SMN2LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101495119-A | Soluble epoxide hydrolase inhibitors | ARETE THERAPEUTICS INC (US) | 2009-07-29 | — | — | CN | claimed |