Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 18/20 | 0.65 |
| ▸ | PGR | P06401 | 2/20 | 0.49 |
| ▸ | AR | P10275 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | SMO | Q99835 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1363786 | 0.79 | NR3C1 (0.85) | NR3C1PGRAR | |
| SCHEMBL12140588 | 0.79 | NR3C1 (0.88) | NR3C1PGRAR | |
| SCHEMBL1363288 | 0.79 | NR3C1 (1.00) | NR3C1PGRAR | |
| SCHEMBL12140592 | 0.78 | NR3C1 (0.78) | NR3C1PGRAR | |
| SCHEMBL1363216 | 0.77 | NR3C1 (0.93) | NR3C1PGR | |
| SCHEMBL3595033 | 0.77 | NR3C1 (0.64) | NR3C1PGRARMAPK1SMO | |
| SCHEMBL12140632 | 0.77 | NR3C1 (0.77) | NR3C1PGRAR | |
| SCHEMBL12140611 | 0.77 | NR3C1 (0.70) | NR3C1PGRAR | |
| SCHEMBL12140591 | 0.76 | NR3C1 (0.82) | NR3C1PGRAR | |
| SCHEMBL12140600 | 0.76 | NR3C1 (0.82) | NR3C1PGRAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101573340-A | Modulators of glucocorticoid receptor AP-1 and/or NF-kB activity and uses thereof | BRISTOL MYERS SQUIBB CO (US) | 2009-11-04 | — | — | CN | disclosed |