Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BIRC2 | Q13490 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
| ▸ | CCR2 | P41597 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | MLNR | O43193 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28129541 | 1.00 | BIRC2 (0.39) | BIRC2MAPTPARP1CCR2KCNH2 | |
| SCHEMBL28179897 | 0.85 | BIRC2 (0.39) | BIRC2MAPT | |
| SCHEMBL28127408 | 0.85 | BIRC2 (0.39) | BIRC2MAPT | |
| SCHEMBL28853916 | 0.82 | BIRC2 (0.37) | BIRC2MAPT | |
| SCHEMBL3106378 | 0.80 | CCR2 (0.38) | BIRC2PARP1CCR2KCNH2 | |
| SCHEMBL27653283 | 0.79 | BIRC2 (0.59) | BIRC2 | |
| SCHEMBL27953215 | 0.79 | BIRC2 (0.59) | BIRC2 | |
| SCHEMBL28141934 | 0.79 | BIRC2 (0.59) | BIRC2 | |
| SCHEMBL294048 | 0.77 | DRD3 (0.34) | — | |
| SCHEMBL28153622 | 0.77 | BIRC2 (0.41) | BIRC2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108137580-A | Fused pyridine derivatives as kinase inhibitors | UCB生物制药私人有限公司 | 2018-06-08 | — | — | CN | disclosed |
| CN-107108579-A | It is used for the derovatives of 5 [(base of piperazine 1) 3 oxopropyls] imidazolidine 2,4 for treating osteoarthritis as ADAMTS inhibitor | 加拉帕戈斯股份有限公司 | 2017-08-29 | — | — | CN | disclosed |
| CN-106559992-A | As the bicyclic heteroaromatic derivative for condensing of kinase inhibitor | UCB生物制药私人有限公司 | 2017-04-05 | — | — | CN | disclosed |
| CN-101479274-A | Pharmaceutical compounds | HOFFMANN LA ROCHE (CH) | 2009-07-08 | — | — | CN | disclosed |