Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.37 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tert-Butyl Formate SCHEMBL27769719 | 1.00 | HTT (0.55) | HTTL3MBTL1ALDH1A1LMNAGAA | |
| SCHEMBL993767 | 0.91 | HTT (0.64) | HTTL3MBTL1ALDH1A1LMNAGAA | |
| SCHEMBL993768 | 0.91 | HTT (0.64) | HTTL3MBTL1ALDH1A1LMNAGAA | |
| Tert-Butyl Formate SCHEMBL27748377 | 0.87 | HTT (0.64) | HTTL3MBTL1ALDH1A1LMNAGAA | |
| Tert-Butyl Formate SCHEMBL27769726 | 0.83 | ALDH1A1 (0.45) | ALDH1A1LMNAHTR1ASLC6A9HTR7 | |
| Tert-Butyl Formate SCHEMBL27769721 | 0.82 | TP53 (0.40) | HTTGAASMN1; SMN2SIGMAR1 | |
| SCHEMBL17690590 | 0.80 | HTT (0.52) | HTTL3MBTL1ALDH1A1LMNAGAA | |
| SCHEMBL18186283 | 0.78 | HTT (0.66) | HTTL3MBTL1ALDH1A1LMNAGAA | |
| SCHEMBL1046568 | 0.76 | HTT (0.67) | HTTL3MBTL1ALDH1A1LMNAGAA | |
| SCHEMBL1046567 | 0.76 | HTT (0.67) | HTTL3MBTL1ALDH1A1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102796099-A | Imidazoquinolines as lipid kinase inhibitors | NOVARTIS AG | 2012-11-28 | — | — | CN | disclosed |
| CN-101495477-A | Imidazoquinolines as lipid kinase inhibitors | NOVARTIS AG (CH) | 2009-07-29 | — | — | CN | disclosed |