Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | AHR | P35869 | 1/20 | 0.45 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | DAO | P14920 | 3/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.39 |
| ▸ | MIF | P14174 | 1/20 | 0.39 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27769602 | 0.83 | TAAR1 (0.46) | TAAR1MAOBDAOMIFUTS2R | |
| SCHEMBL28784749 | 0.83 | TAAR1 (0.48) | TAAR1MAOBDAOMIF | |
| SCHEMBL5785203 | 0.83 | TAAR1 (0.42) | KCNH2TMEM97TAAR1P2RX3MAOB | |
| SCHEMBL27811355 | 0.81 | MAPT (0.46) | TMEM97TAAR1CNR1 | |
| SCHEMBL27790955 | 0.78 | TAAR1 (0.43) | KCNH2TAAR1AHRMAOBDAO | |
| SCHEMBL3729914 | 0.77 | MAOB (0.55) | TAAR1MAOB | |
| SCHEMBL27811353 | 0.77 | DAO (0.41) | KCNH2CNR1DAOCNR2 | |
| SCHEMBL790207 | 0.76 | TAAR1 (0.47) | TAAR1AHRMAOBHIF1AEPAS1 | |
| SCHEMBL3743690 | 0.75 | KIF11 (0.60) | TAAR1MAOB | |
| SCHEMBL3732183 | 0.75 | KIF11 (0.60) | TAAR1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101627007-A | Aminoamides as orexin antagonists | HOFFMANN LA ROCHE | 2010-01-13 | — | — | CN | disclosed |