Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | USP2 | O75604 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MC4R | P32245 | 1/20 | 0.36 |
| ▸ | TMPRSS11D | O60235 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1735666 | 0.84 | TP53 (0.46) | LMNAMAPTUSP2MEN1KMT2A | |
| SCHEMBL1735658 | 0.84 | TP53 (0.46) | LMNAMAPTUSP2MEN1KMT2A | |
| SCHEMBL1735732 | 0.80 | LMNA (0.50) | LMNAMAPTUSP2MEN1KMT2A | |
| SCHEMBL1735731 | 0.80 | LMNA (0.50) | LMNAMAPTUSP2MEN1KMT2A | |
| SCHEMBL1734763 | 0.80 | MAPT (0.47) | LMNAMAPTUSP2MEN1KMT2A | |
| SCHEMBL1734761 | 0.80 | MAPT (0.47) | LMNAMAPTUSP2MEN1KMT2A | |
| SCHEMBL27806677 | 0.76 | MAPT (0.42) | LMNAMAPTUSP2MEN1KMT2A | |
| SCHEMBL1734616 | 0.76 | MAPT (0.46) | LMNAMAPTUSP2MEN1KMT2A | |
| SCHEMBL1734619 | 0.76 | MAPT (0.46) | LMNAMAPTUSP2MEN1KMT2A | |
| SCHEMBL1734705 | 0.74 | MAPT (0.44) | LMNAMAPTUSP2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101641348-A | Imidazolidinone derivatives | HOFFMANN LA ROCHE CH | 2010-02-03 | — | — | CN | claimed |
| CN-101641348-B | Imidazolidinone derivatives | HOFFMANN LA ROCHE | 2014-09-10 | — | — | CN | disclosed |
| CN-101641348-A | Imidazolidinone derivatives | HOFFMANN LA ROCHE CH | 2010-02-03 | — | — | CN | disclosed |