Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA5A | P35218 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.48 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.43 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.43 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.43 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.38 |
| ▸ | KLKB1 | P03952 | 3/20 | 0.37 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | CLK2 | P49760 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.37 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.37 |
| ▸ | GLS | O94925 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3096972 | 0.78 | PIK3CD (0.65) | CA12CA1CA2CA5ACA9 | |
| SCHEMBL6854674 | 0.69 | NOTUM (0.51) | CHRM1LMNABRS3 | |
| SCHEMBL323044 | 0.69 | NOTUM (0.55) | MAP4K4LMNAMGLL | |
| SCHEMBL5717609 | 0.68 | KDM4E (0.50) | CA12CA1CA2CA5ACA9 | |
| SCHEMBL28011535 | 0.68 | PPARG (0.48) | CHRM1LMNABRS3 | |
| SCHEMBL7891506 | 0.67 | FFAR1 (0.51) | LMNA | |
| SCHEMBL1177658 | 0.67 | NSD2 (0.57) | CA12CA1CA2CA5ACA9 | |
| SCHEMBL261444 | 0.66 | HRH2 (0.38) | HRH2 | |
| SCHEMBL10029392 | 0.66 | NOTUM (0.55) | CHRM1MGLLBRS3 | |
| SCHEMBL18756509 | 0.66 | CHRM1 (0.65) | CA12CA1CA2CA5ACA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101479258-A | Thiazolyl urea derivatives as phosphatidylinositol 3-kinase inhibitors | NOVARTIS AG (CH) | 2009-07-08 | — | — | CN | disclosed |