SCHEMBL27770325

SCHEMBL27770325

COOC(OC)(c1ccccc1)c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.46
CES1 P23141 1/20 0.39
KCNN4 O15554 4/20 0.39
ALDH1A1 P00352 4/20 0.38
ALOX15 P16050 1/20 0.38
CA4 P22748 2/20 0.36
CA12 O43570 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA7 P43166 1/20 0.36
CA9 Q16790 1/20 0.36
CA14 Q9ULX7 1/20 0.36
KMT2A Q03164 2/20 0.35
MAPT P10636 1/20 0.35
LMNA P02545 1/20 0.35
TSHR P16473 2/20 0.35
TAAR1 Q96RJ0 1/20 0.33
GAA P10253 1/20 0.33
KDM4E B2RXH2 1/20 0.33
MEN1 O00255 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7873640 0.90 MAPK1 (0.50) MAPK1CES1KCNN4ALDH1A1ALOX15
SCHEMBL240092 0.85 MAPK1 (0.48) MAPK1CES1KCNN4ALDH1A1ALOX15
SCHEMBL2790917 0.80 MAPK1 (0.44) MAPK1CES1KCNN4ALDH1A1ALOX15
SCHEMBL3022980 0.75 MAPK1 (0.50) MAPK1CES1KCNN4ALDH1A1ALOX15
SCHEMBL9508370 0.73 MAPK1 (0.76) MAPK1CES1KCNN4ALDH1A1ALOX15
SCHEMBL7873647 0.73 MAPK1 (0.54) MAPK1CES1KCNN4ALDH1A1ALOX15
SCHEMBL28502798 0.73 CA4 (0.54) CES1CA4CA12CA1CA2
SCHEMBL5544706 0.73 MAPK1 (0.38) MAPK1CES1KCNN4ALDH1A1ALOX15
SCHEMBL27619064 0.73 MAPK1 (0.38) MAPK1CES1KCNN4ALDH1A1ALOX15
SCHEMBL11122765 0.73 CES1 (0.41) MAPK1CES1KCNN4ALDH1A1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116715563-B Method for synthesizing diphenyl methane compounds and diphenyl ketone compounds by catalyzing diphenyl methanol compounds through zeolite 常州大学 2025-02-25 CN disclosed
CN-116333002-A Symmetrical alpha-diimine nickel complex and preparation method and application thereof 山西大学 2023-06-27 CN disclosed
CN-113816837-A Synthesis method of 4,4' -dimethoxy triphenylchloromethane 连云港冠昕医药科技有限公司 2021-12-21 CN disclosed
CN-105164789-B Resist patterns forming method, resist sub-image forming apparatus, Resist patterns forming apparatus and anticorrosive additive material 国立大学法人大阪大学 2018-04-20 CN disclosed
CN-105164789-A Method of forming resist pattern, device for forming resist latent image, device for forming resist pattern, and resist material UNIV OSAKA NAT UNIV CORP 2015-12-16 CN disclosed
CN-101479243-B Glycine transporter-1 inhibitors AMGEN INC 2013-01-02 CN disclosed
CN-101479243-A Glycine transporter-1 inhibitors AMGEN INC (US) 2009-07-08 CN disclosed