Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | KCNN4 | O15554 | 5/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 2/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18429814 | 0.87 | CA4 (0.50) | MAPK1KIF11CES1CA4 | |
| SCHEMBL297786 | 0.83 | MAPK1 (0.52) | MAPK1KCNN4KIF11ALDH1A1ALOX15 | |
| SCHEMBL5914847 | 0.81 | MAPK1 (0.39) | MAPK1KCNN4KIF11ALDH1A1ALOX15 | |
| SCHEMBL5583968 | 0.80 | CA1 (0.43) | MAPK1KIF11ALDH1A1MEN1KMT2A | |
| SCHEMBL7873640 | 0.79 | MAPK1 (0.50) | MAPK1KCNN4ALDH1A1ALOX15KMT2A | |
| SCHEMBL11558547 | 0.78 | MAPK1 (0.48) | MAPK1KCNN4KIF11ALDH1A1ALOX15 | |
| Methoxytriphenylmethane SCHEMBL9103 | 0.78 | MAPK1 (0.48) | MAPK1KCNN4KIF11ALDH1A1ALOX15 | |
| SCHEMBL7873647 | 0.77 | MAPK1 (0.54) | MAPK1KCNN4ALDH1A1ALOX15KMT2A | |
| SCHEMBL9508370 | 0.77 | MAPK1 (0.76) | MAPK1KCNN4ALDH1A1ALOX15KMT2A | |
| SCHEMBL11639499 | 0.77 | MAPK1 (0.54) | MAPK1KCNN4KIF11ALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 105 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109705124-A | A kind of labeled with radioactive fluorine Larotrectinib compound and preparation method thereof | 上海健康医学院 | 2019-05-03 | — | — | CN | claimed |
| CN-1117760-C | Lysosomal enzyme-cleavable antitumor drug conjugates | BRISTOL MYERS SQUIBB CO (US) | 2003-08-13 | — | — | CN | claimed |
| CN-1100426-A | Lysosomal enzyme-cleavable antitumor drug conjugates | BRISTOL MYERS SQUIBB CO (US) | 1995-03-22 | — | — | CN | claimed |
| US-20240018489-A1 | BIOCATALYSTS FOR THE PREPARATION OF HYDROXY SUBSTITUTED CARBAMATES | INNOVATUS LIFE SCIENCES LENDING FUND I, LP, AS COLLATERAL AGENT | 2024-01-18 | — | — | US | disclosed |
| US-11713451-B2 | Biocatalysts for the preparation of hydroxy substituted carbamates | CODEXIS, INC. (US) | 2023-08-01 | — | — | US | disclosed |
| US-20210071151-A1 | BIOCATALYSTS FOR THE PREPARATION OF HYDROXY SUBSTITUTED CARBAMATES | INNOVATUS LIFE SCIENCES LENDING FUND I, LP, AS COLLATERAL AGENT | 2021-03-11 | — | — | US | disclosed |
| US-10851351-B2 | Biocatalysts for the preparation of hydroxy substituted carbamates | CODEXIS, INC. (US) | 2020-12-01 | — | — | US | disclosed |
| EP-2780448-B1 | BIOCATALYSTS FOR THE PREPARATION OF HYDROXY SUBSTITUTED CARBAMATES | CODEXIS INC (US) | 2019-09-11 | — | — | EP | disclosed |
| US-20190177702-A1 | BIOCATALYSTS FOR THE PREPARATION OF HYDROXY SUBSTITUTED CARBAMATES | INNOVATUS LIFE SCIENCES LENDING FUND I, LP, AS COLLATERAL AGENT | 2019-06-13 | — | — | US | disclosed |
| CN-109705124-A | A kind of labeled with radioactive fluorine Larotrectinib compound and preparation method thereof | 上海健康医学院 | 2019-05-03 | — | — | CN | disclosed |
| US-10253303-B2 | Biocatalysts for the preparation of hydroxy substituted carbamates | CODEXIS, INC. (US) | 2019-04-09 | — | — | US | disclosed |
| WO-2008019784-A2 | AVERMECTIN DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2008-02-21 | — | — | WO | disclosed |
| WO-2008011033-A2 | SYNTHESIS OF ISOTOPICALLY LABELED ALPHA-KETO ACIDS AND ESTERS | SPECTRA GASES, INC. (US) | 2008-01-24 | — | — | WO | disclosed |
| WO-2006098705-A1 | PROCESS FOR PRODUCING BIPHENYL-TETRAZOLE COMPOUNDS | ULKAR KIMYA SANAYII VE TICARET AS (TR) | 2006-09-21 | — | — | WO | disclosed |
| EP-1447408-A1 | Amino acid loaded trityl alcohol resins, method of production of amino acid loaded trityl alcohol resins and therapeutics produced therewith | Rohm and Haas Company (US) | 2004-08-18 | — | — | EP | disclosed |
| US-20040158037-A1 | Amino acid loaded trityl alcohol resins, method of production of amino acid loaded trityl alcohol resins and biologically active substances and therapeutics produced therewith | BOHLING JAMES CHARLES (US) | 2004-08-12 | — | — | US | disclosed |
| CN-87105787-A | The thermostability enzyme of purifying and with its increase, the method for detection and/or cloning nucleic acid sequences | — | 1988-05-11 | — | — | CN | disclosed |
| CN-87101691-A | Carbocyclic purine nucleosides, their preparation and application | — | 1987-10-07 | — | — | CN | disclosed |
| US-4152524-A | BRONCHODILATORS, HYPOTENSIVE | AMERICAN CYANAMID COMPANY (US) | 1979-05-01 | — | — | US | disclosed |
| US-4076947-A | BRONCHODILATORS, HYPOTENSIVE AGENTS, ANTIULCER AGENTS | AMERICAN CYANAMID COMPANY (US) | 1978-02-28 | — | — | US | disclosed |