Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.58 |
| ▸ | EGFR | P00533 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | NOX4 | Q9NPH5 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | RGS12 | O14924 | 1/20 | 0.55 |
| ▸ | LCK | P06239 | 1/20 | 0.55 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.55 |
| ▸ | ALB | P02768 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | LDHA | P00338 | 1/20 | 0.50 |
| ▸ | LDHB | P07195 | 1/20 | 0.50 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | CRHBP | P24387 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27749183 | 0.91 | EGFR (0.67) | APPEGFRMAPTNOX4ALDH1A1 | |
| SCHEMBL22624722 | 0.81 | MAPT (0.55) | APPEGFRMAPTTDP1ALB | |
| SCHEMBL3294789 | 0.81 | MAPT (0.57) | MAPTALDH1A1TDP1KMT2AMEN1 | |
| SCHEMBL7809216 | 0.81 | EGFR (0.81) | EGFRMAPTNOX4ALDH1A1TDP1 | |
| SCHEMBL22624739 | 0.81 | APP (0.65) | APPEGFRMAPTALDH1A1TDP1 | |
| SCHEMBL22624810 | 0.80 | APP (0.63) | APPEGFRTDP1ALBKMT2A | |
| SCHEMBL22624691 | 0.79 | APP (0.66) | APPEGFRMAPTALDH1A1ALB | |
| SCHEMBL22624806 | 0.79 | APP (0.66) | APPEGFRMAPTALDH1A1ALB | |
| SCHEMBL22624811 | 0.79 | APP (0.66) | APPEGFRMAPTALDH1A1ALB | |
| SCHEMBL27770270 | 0.79 | EGFR (0.60) | APPEGFRMAPTNOX4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101492384-A | Uses of aminosalicylic acid derivative as neuroprotective agent | UNIV NANJING MEDICAL (CN) | 2009-07-29 | — | — | CN | disclosed |