Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 8/20 | 0.60 |
| ▸ | NOX4 | Q9NPH5 | 2/20 | 0.60 |
| ▸ | RGS12 | O14924 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | LCK | P06239 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.59 |
| ▸ | CA1 | P00915 | 2/20 | 0.58 |
| ▸ | CA2 | P00918 | 2/20 | 0.58 |
| ▸ | CA12 | O43570 | 1/20 | 0.58 |
| ▸ | CA9 | Q16790 | 1/20 | 0.58 |
| ▸ | SYK | P43405 | 2/20 | 0.49 |
| ▸ | APP | P05067 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | LDHA | P00338 | 1/20 | 0.46 |
| ▸ | LDHB | P07195 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27787480 | 0.90 | EGFR (0.74) | EGFRNOX4RGS12ALDH1A1LCK | |
| SCHEMBL16005376 | 0.86 | KDM4C (0.50) | EGFRNOX4RGS12ALDH1A1LCK | |
| SCHEMBL7809216 | 0.86 | EGFR (0.81) | EGFRNOX4RGS12ALDH1A1LCK | |
| Lysine SCHEMBL27809453 | 0.85 | CA12 (0.47) | EGFRNOX4RGS12ALDH1A1LCK | |
| SCHEMBL27770271 | 0.83 | EGFR (0.60) | EGFRNOX4RGS12ALDH1A1LCK | |
| SCHEMBL27749184 | 0.83 | EGFR (0.60) | EGFRNOX4RGS12ALDH1A1LCK | |
| SCHEMBL27809392 | 0.83 | EGFR (0.51) | EGFRNOX4RGS12ALDH1A1LCK | |
| SCHEMBL11241726 | 0.83 | CA1 (0.65) | EGFRNOX4RGS12ALDH1A1LCK | |
| SCHEMBL27787484 | 0.82 | EGFR (0.56) | EGFRNOX4RGS12ALDH1A1LCK | |
| SCHEMBL7809127 | 0.81 | NOX4 (0.78) | EGFRNOX4RGS12ALDH1A1LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101792399-A | Aminosalicylic acid derivative lysine complex salt, preparation method and application thereof | UNIV NANJING MEDICAL | 2010-08-04 | — | — | CN | disclosed |
| CN-101492384-A | Uses of aminosalicylic acid derivative as neuroprotective agent | UNIV NANJING MEDICAL (CN) | 2009-07-29 | — | — | CN | disclosed |