Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.36 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16746561 | 0.79 | CYP1A2 (0.43) | HTTDOT1LNISCHMAPTALDH1A1 | |
| SCHEMBL22512241 | 0.75 | CYP3A4 (0.36) | MAPTALDH1A1KDM4EUSP2POLB | |
| SCHEMBL29661766 | 0.73 | MEN1 (0.50) | MAPTALDH1A1KDM4EPOLBHPGD | |
| SCHEMBL5914549 | 0.73 | MEN1 (0.50) | MAPTALDH1A1KDM4EPOLBHPGD | |
| SCHEMBL100946 | 0.72 | — | — | |
| SCHEMBL9232217 | 0.71 | MAPT (0.53) | HTTNISCHMAPTALDH1A1KDM4E | |
| SCHEMBL30368237 | 0.71 | MAPT (0.53) | HTTNISCHMAPTALDH1A1KDM4E | |
| SCHEMBL21395985 | 0.71 | ESR1 (0.40) | HTTDOT1LALDH1A1KDM4ERAB9A | |
| SCHEMBL3787606 | 0.71 | MAPT (0.44) | HTTDOT1LMAPTALDH1A1KDM4E | |
| SCHEMBL3792624 | 0.71 | RAPGEF4 (0.40) | MAPTALDH1A1KDM4EUSP2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101495120-A | Composition for induction or inhibition of stem cell differentiation | CHOONGWAE PHARMA CORP (KR) | 2009-07-29 | — | — | CN | disclosed |