Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | BCL9 | O00512 | 1/20 | 0.39 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27776087 | 0.87 | HTR7 (0.49) | HTR7CHRNB2CHRNA4ALOX15KMT2A | |
| SCHEMBL27725679 | 0.82 | F2 (0.41) | CHRNB2CHRNA4BCL9CTNNB1ALOX15 | |
| SCHEMBL7982993 | 0.81 | KDM4E (0.39) | BCL9CTNNB1ALOX15KMT2ARAB9A | |
| SCHEMBL27545434 | 0.78 | MAPK8 (0.46) | BCL9CTNNB1ALOX15KMT2ARAB9A | |
| SCHEMBL27585578 | 0.78 | HTR7 (0.45) | HTR7CHRNB2CHRNA4ALDH1A1KDM4E | |
| SCHEMBL27535055 | 0.77 | MAPK8 (0.48) | CHRNB2CHRNA4BCL9CTNNB1ALOX15 | |
| SCHEMBL248107 | 0.75 | HTR7 (0.42) | HTR7CHRNB2CHRNA4ALOX15ALDH1A1 | |
| SCHEMBL5200121 | 0.74 | MEN1 (0.44) | HTR7CHRNB2CHRNA4KMT2AALDH1A1 | |
| SCHEMBL8772213 | 0.74 | HTR7 (0.41) | HTR7CHRNB2CHRNA4ALOX15ALDH1A1 | |
| SCHEMBL700968 | 0.73 | PDE4A (0.45) | BCL9CTNNB1ALOX15KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114502158-A | IRAK degradation agent and application thereof | 凯麦拉医疗公司 | 2022-05-13 | — | — | CN | disclosed |
| CN-101432284-A | Dihydropyrazolopyrimidinone derivative | BANYU PHARMA CO LTD (JP) | 2009-05-13 | — | — | CN | disclosed |