Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.33 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.33 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.33 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13771807 | 0.85 | SMYD3 (0.42) | CYP11B2HTTCA2POLB | |
| SCHEMBL15006445 | 0.81 | HCAR2 (0.46) | CYP11B2HTTCA2CYP11B1 | |
| SCHEMBL29658575 | 0.81 | HCAR2 (0.46) | CYP11B2HTTCA2CYP11B1 | |
| SCHEMBL22265815 | 0.78 | CA2 (0.45) | CA2POLB | |
| SCHEMBL29351393 | 0.78 | CA2 (0.45) | CA2POLB | |
| SCHEMBL12598886 | 0.78 | HCAR2 (0.47) | CYP11B2CYP11B1 | |
| SCHEMBL27896449 | 0.78 | POLB (0.42) | CYP11B2CYP11B1POLB | |
| SCHEMBL2782806 | 0.77 | KDM4E (0.49) | CYP11B2HTTCA2POLB | |
| SCHEMBL31425224 | 0.77 | KDM4E (0.49) | CYP11B2HTTCA2POLB | |
| SCHEMBL3372685 | 0.77 | HCAR2 (0.46) | MKNK1MKNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101489558-A | Acetylenic heteroaryl compounds | ARIAD PHARMA INC (US) | 2009-07-22 | — | — | CN | disclosed |