Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.60 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.55 |
| ▸ | CDK2 | P24941 | 4/20 | 0.54 |
| ▸ | CDK1 | P06493 | 3/20 | 0.54 |
| ▸ | GSK3B | P49841 | 3/20 | 0.54 |
| ▸ | IGF1R | P08069 | 2/20 | 0.54 |
| ▸ | AURKA | O14965 | 2/20 | 0.54 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.54 |
| ▸ | JAK2 | O60674 | 2/20 | 0.54 |
| ▸ | LYN | P07948 | 2/20 | 0.54 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.54 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.54 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.54 |
| ▸ | MARK3 | P27448 | 2/20 | 0.54 |
| ▸ | BLK | P51451 | 2/20 | 0.54 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.54 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.54 |
| ▸ | ERBB4 | Q15303 | 2/20 | 0.54 |
| ▸ | MARK2 | Q7KZI7 | 2/20 | 0.54 |
| ▸ | PLK3 | Q9H4B4 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL167891 | 1.00 | MAP3K5 (0.60) | MAP3K5ROCK1CDK2CDK1GSK3B | |
| SCHEMBL31381352 | 1.00 | MAP3K5 (0.60) | MAP3K5ROCK1CDK2CDK1GSK3B | |
| Benzene SCHEMBL28188863 | 1.00 | MAP3K5 (0.60) | MAP3K5ROCK1CDK2CDK1GSK3B | |
| SCHEMBL4573935 | 0.98 | MAP3K5 (0.58) | MAP3K5ROCK1CDK2CDK1GSK3B | |
| Hydrochloric Acid SCHEMBL8807679 | 0.98 | MAP3K5 (0.58) | MAP3K5ROCK1CDK2CDK1GSK3B | |
| Quinoline SCHEMBL28107595 | 0.90 | ALDH1A1 (0.53) | MAP3K5ROCK1CDK2CDK1GSK3B | |
| SCHEMBL6467426 | 0.88 | MAP3K5 (0.54) | MAP3K5ROCK1CDK2CDK1GSK3B | |
| SCHEMBL3338544 | 0.86 | AURKA (0.57) | MAP3K5ROCK1CDK2CDK1GSK3B | |
| SCHEMBL3339632 | 0.86 | NPY5R (0.55) | MAP3K5ROCK1CDK2CDK1AURKA | |
| SCHEMBL6037487 | 0.86 | ROCK1 (0.53) | MAP3K5ROCK1CDK2CDK1GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102586431-A | Method to determine responsiveness of cancer to epidermal growth factor receptor targeting treatments | GEN HOSPITAL CORP | 2012-07-18 | — | — | CN | disclosed |
| CN-101501211-A | Method for Determining Responsiveness of Cancer to Epidermal Growth Factor Receptor Targeted Therapy | GEN HOSPITAL CORP (US) | 2009-08-05 | — | — | CN | disclosed |