Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | PTGER1 | P34995 | 8/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27749426 | 0.86 | THRB (0.52) | THRBPTGER1HTTLMNAGAA | |
| SCHEMBL27749658 | 0.85 | PTGER1 (0.51) | THRBPTGER1HTTLMNAGAA | |
| SCHEMBL27770495 | 0.85 | THRB (0.45) | THRBPTGER1HTTLMNAGAA | |
| SCHEMBL2176598 | 0.84 | PTGER1 (0.53) | THRBPTGER1HTTLMNAALDH1A1 | |
| SCHEMBL2179619 | 0.84 | THRB (0.57) | THRBPTGER1HTTLMNAALDH1A1 | |
| SCHEMBL2173313 | 0.84 | THRB (0.54) | THRBPTGER1LMNAGAASMN1; SMN2 | |
| SCHEMBL2175975 | 0.84 | THRB (0.57) | THRBPTGER1HTTLMNAALDH1A1 | |
| SCHEMBL27749431 | 0.82 | PTGER1 (0.51) | THRBPTGER1HTTGAAALDH1A1 | |
| SCHEMBL27749427 | 0.82 | PTGER1 (0.50) | THRBPTGER1HTTLMNAGAA | |
| SCHEMBL2175955 | 0.82 | PTGER1 (0.55) | THRBPTGER1SMN1; SMN2RORCMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101500554-B | Sulfonamide compound or salt thereof | ASTELLAS PHARMA INC | 2012-06-27 | — | — | CN | claimed |
| CN-101500554-A | Sulfonamide compound or salt thereof | ASTELLAS PHARMA INC (JP) | 2009-08-05 | — | — | CN | claimed |
| CN-101500554-B | Sulfonamide compound or salt thereof | ASTELLAS PHARMA INC | 2012-06-27 | — | — | CN | disclosed |
| CN-101500554-A | Sulfonamide compound or salt thereof | ASTELLAS PHARMA INC (JP) | 2009-08-05 | — | — | CN | disclosed |