Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | MAOA | P21397 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.33 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.33 |
| ▸ | ALPL | P05186 | 1/20 | 0.33 |
| ▸ | XIAP | P98170 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8000746 | 0.83 | KMT2A (0.41) | MAPTNPC1RAB9AALDH1A1TDP1 | |
| SCHEMBL26108874 | 0.78 | CYP3A4 (0.48) | MAPTNPC1RAB9ACYP19A1ALDH1A1 | |
| SCHEMBL7822792 | 0.78 | GAA (0.40) | MAPTNPC1RAB9AALDH1A1MAPK1 | |
| SCHEMBL2284325 | 0.73 | TDP1 (0.46) | MAPTNPC1RAB9ACYP19A1ALDH1A1 | |
| SCHEMBL28232904 | 0.73 | KMT2A (0.51) | MAPTNPC1RAB9AALDH1A1TDP1 | |
| SCHEMBL28168615 | 0.72 | TDP1 (0.48) | MAPTNPC1RAB9AALDH1A1CYP3A4 | |
| SCHEMBL7835448 | 0.72 | RAB9A (0.42) | MAPTNPC1RAB9AALDH1A1TDP1 | |
| SCHEMBL19998352 | 0.70 | CYP3A4 (0.37) | MAPTNPC1RAB9AALDH1A1CYP3A4 | |
| SCHEMBL8581201 | 0.70 | KMT2A (0.50) | MAPTALDH1A1CYP3A4TDP1MAPK1 | |
| SCHEMBL27258081 | 0.70 | RAB9A (0.47) | NPC1RAB9AALDH1A1TDP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101489555-A | Nf-kappa | OTSUKA PHARMA CO LTD (JP) | 2009-07-22 | — | — | CN | disclosed |