1-Hydroxy-3-Methoxybenzene

1-Hydroxy-3-Methoxybenzene

SCHEMBL27770537

CO.COc1cccc(O)c1

nearest known ligand 0.62

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.62
ESR2 Q92731 1/20 0.62
GABRA1 P14867 1/20 0.56
GABRG2 P18507 1/20 0.56
GABRB3 P28472 1/20 0.56
GABRA3 P34903 1/20 0.56
GABRA2 P47869 1/20 0.56
GABRB2 P47870 1/20 0.56
CYP3A4 P08684 3/20 0.55
ABL1 P00519 1/20 0.55
BCR P11274 1/20 0.55
ACHE P22303 1/20 0.54
CA2 P00918 2/20 0.52
CA9 Q16790 2/20 0.52
ALDH1A1 P00352 2/20 0.52
CA1 P00915 1/20 0.52
CA7 P43166 1/20 0.52
CES2 O00748 1/20 0.52
CES1 P23141 1/20 0.52
ENPP2 Q13822 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
1-Hydroxy-3-Methoxybenzene SCHEMBL29421717 0.98
1-Hydroxy-3-Methoxybenzene SCHEMBL28256 0.98
1-Hydroxy-3-Methoxybenzene SCHEMBL6760019 0.95 ESR1 (0.62) ESR1ESR2GABRA1GABRG2GABRB3
1-Hydroxy-3-Methoxybenzene SCHEMBL27446904 0.95 ESR1 (0.62) ESR1ESR2GABRA1GABRG2GABRB3
1-Hydroxy-3-Methoxybenzene SCHEMBL28322080 0.95 ESR1 (0.62) ESR1ESR2GABRA1GABRG2GABRB3
1-Hydroxy-3-Methoxybenzene SCHEMBL7390774 0.95 ESR1 (0.62) ESR1ESR2GABRA1GABRG2GABRB3
1-Hydroxy-3-Methoxybenzene SCHEMBL11366240 0.93 ESR1 (0.61) ESR1ESR2GABRA1GABRG2GABRB3
1-Hydroxy-3-Methoxybenzene SCHEMBL11366244 0.93 ESR1 (0.61) ESR1ESR2GABRA1GABRG2GABRB3
1-Hydroxy-3-Methoxybenzene SCHEMBL9623569 0.91 ESR1 (0.59) ESR1ESR2GABRA1GABRG2GABRB3
1-Hydroxy-3-Methoxybenzene SCHEMBL27611510 0.91 ESR1 (0.64) ESR1ESR2GABRA1GABRG2GABRB3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106187718-B A kind of preparation method of vanillic aldehyde 上海应用技术学院 2019-05-31 CN claimed
CN-106187718-A A kind of preparation method of vanillin 上海应用技术学院 2016-12-07 CN claimed
CN-101486630-B Catalytic synthesizing process of 3-methoxy-4-phenol methanol UNIV EAST CHINA SCIENCE & TECH 2013-06-12 CN claimed
CN-106187718-B A kind of preparation method of vanillic aldehyde 上海应用技术学院 2019-05-31 CN disclosed
CN-106187718-B A kind of preparation method of vanillic aldehyde 上海应用技术学院 2019-05-31 CN disclosed
CN-106187718-A A kind of preparation method of vanillin 上海应用技术学院 2016-12-07 CN disclosed
CN-101486630-B Catalytic synthesizing process of 3-methoxy-4-phenol methanol UNIV EAST CHINA SCIENCE & TECH 2013-06-12 CN disclosed
CN-101486630-B Catalytic synthesizing process of 3-methoxy-4-phenol methanol UNIV EAST CHINA SCIENCE & TECH 2013-06-12 CN disclosed
CN-101486630-A Catalytic synthesizing process of 3-methoxy-4-phenol methanol UNIV EAST CHINA SCIENCE & TECH (CN) 2009-07-22 CN disclosed