Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.59 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.59 |
| ▸ | CA4 | P22748 | 2/20 | 0.54 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.53 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.53 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.53 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.53 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.53 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | ABL1 | P00519 | 2/20 | 0.52 |
| ▸ | BCR | P11274 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 1,3-Dimethoxybenzene SCHEMBL28094887 | 0.93 | MAOB (0.60) | ESR1ESR2CA4MAOBNPC1 | |
| 1-Hydroxy-3-Methoxybenzene SCHEMBL29421717 | 0.93 | — | — | |
| 1-Hydroxy-3-Methoxybenzene SCHEMBL28256 | 0.93 | — | — | |
| Biphenyl SCHEMBL28999514 | 0.92 | ESR1 (0.56) | ESR1ESR2CA4MAOBNPC1 | |
| 1-Hydroxy-3-Methoxybenzene SCHEMBL28322080 | 0.91 | ESR1 (0.62) | ESR1ESR2NPC1RAB9AGABRA1 | |
| 1-Hydroxy-3-Methoxybenzene SCHEMBL27446904 | 0.91 | ESR1 (0.62) | ESR1ESR2NPC1RAB9AGABRA1 | |
| 1-Hydroxy-3-Methoxybenzene SCHEMBL27770537 | 0.91 | ESR1 (0.62) | ESR1ESR2NPC1RAB9AGABRA1 | |
| 1-Hydroxy-3-Methoxybenzene SCHEMBL6760019 | 0.91 | ESR1 (0.62) | ESR1ESR2NPC1RAB9AGABRA1 | |
| 1-Hydroxy-3-Methoxybenzene SCHEMBL7390774 | 0.91 | ESR1 (0.62) | ESR1ESR2NPC1RAB9AGABRA1 | |
| Mequinol SCHEMBL7759397 | 0.89 | ESR2 (0.59) | ESR1ESR2GABRA1GABRG2GABRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110382501-A | Benzodiazepine derivatives, compositions and methods for treating cognitive impairment | 艾吉因生物股份有限公司 | 2019-10-25 | — | — | CN | disclosed |
| CN-105228449-A | Antimicrobial compositions containing glycerin ether | SYMRISE AG | 2016-01-06 | — | — | CN | disclosed |
| CN-101255152-A | Preparation method and use of piperazine having cytotoxic activity | WENZHOU MEDICAL COLLEGE (CN) | 2008-09-03 | — | — | CN | disclosed |
| EP-0212944-B1 | MELT-PROCESSABLE AROMATIC COPOLYESTER | Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo (JP) | 1992-04-08 | — | — | EP | disclosed |
| US-4746721-A | ENGINEERING PLASTICS | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) | 1988-05-24 | — | — | US | disclosed |
| EP-0212944-A2 | Melt-processable aromatic copolyester | Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo (JP) | 1987-03-04 | — | — | EP | disclosed |