Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.55 |
| ▸ | NPC1 | O15118 | 8/20 | 0.55 |
| ▸ | CASP1 | P29466 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.51 |
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL95346 | 0.88 | RAB9A (0.62) | RAB9ANPC1CASP1SMN1; SMN2HPGD | |
| SCHEMBL96375 | 0.86 | RAB9A (0.68) | RAB9ANPC1CASP1SMN1; SMN2HPGD | |
| SCHEMBL96399 | 0.84 | NPC1 (0.48) | RAB9ANPC1CASP1SMN1; SMN2HPGD | |
| SCHEMBL8240402 | 0.83 | NPC1 (0.56) | RAB9ANPC1CASP1SMN1; SMN2HPGD | |
| SCHEMBL94714 | 0.82 | SMN1; SMN2 (0.67) | RAB9ANPC1CASP1SMN1; SMN2HPGD | |
| SCHEMBL4843520 | 0.81 | RAB9A (0.67) | RAB9ANPC1CASP1SMN1; SMN2HPGD | |
| SCHEMBL2056347 | 0.80 | RAB9A (0.61) | RAB9ANPC1CASP1SMN1; SMN2HPGD | |
| SCHEMBL2054645 | 0.79 | SMN1; SMN2 (0.56) | RAB9ANPC1CASP1SMN1; SMN2HPGD | |
| SCHEMBL94767 | 0.79 | SMN1; SMN2 (0.46) | RAB9ANPC1CASP1SMN1; SMN2HPGD | |
| SCHEMBL95621 | 0.79 | SMN1; SMN2 (0.46) | RAB9ANPC1CASP1SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101489555-A | Nf-kappa | OTSUKA PHARMA CO LTD (JP) | 2009-07-22 | — | — | CN | disclosed |