Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | GAA | P10253 | 3/20 | 0.67 |
| ▸ | TP53 | P04637 | 2/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29414304 | 0.91 | MAPT (0.80) | MAPTSMN1; SMN2ALDH1A1GAATP53 | |
| SCHEMBL338616 | 0.91 | MAPT (0.80) | MAPTSMN1; SMN2ALDH1A1GAATP53 | |
| SCHEMBL501813 | 0.85 | MAPT (0.77) | MAPTSMN1; SMN2ALDH1A1GAATP53 | |
| SCHEMBL29384309 | 0.85 | MAPT (0.77) | MAPTSMN1; SMN2ALDH1A1GAATP53 | |
| SCHEMBL30190508 | 0.84 | MAPT (0.69) | MAPTSMN1; SMN2ALDH1A1GAATP53 | |
| SCHEMBL8005673 | 0.84 | MAPT (0.69) | MAPTSMN1; SMN2ALDH1A1GAATP53 | |
| Benzophenone SCHEMBL27403393 | 0.84 | MAPT (0.74) | MAPTSMN1; SMN2ALDH1A1GAATP53 | |
| SCHEMBL28351687 | 0.82 | MAPT (0.78) | MAPTSMN1; SMN2ALDH1A1GAATP53 | |
| Urea SCHEMBL28117653 | 0.81 | MAPT (0.65) | MAPTSMN1; SMN2ALDH1A1GAATP53 | |
| SCHEMBL1227388 | 0.81 | MAPT (1.00) | MAPTSMN1; SMN2ALDH1A1GAATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101489555-A | Nf-kappa | OTSUKA PHARMA CO LTD (JP) | 2009-07-22 | — | — | CN | disclosed |