Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A1 | P18405 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.45 |
| ▸ | NAMPT | P43490 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.42 |
| ▸ | MLNR | O43193 | 2/20 | 0.42 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.41 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2776630 | 1.00 | SRD5A1 (0.46) | SRD5A1HRH3ADRB2NAMPTPOLB | |
| SCHEMBL2775789 | 0.88 | HRH1 (0.45) | SRD5A1HRH3ADRB2NAMPTPOLB | |
| SCHEMBL2775725 | 0.83 | DPP4 (0.49) | SRD5A1HRH3ADRB2NAMPTEPHX2 | |
| SCHEMBL27805791 | 0.83 | SRD5A1 (0.49) | SRD5A1HRH3ADRB2NAMPTPOLB | |
| SCHEMBL27805792 | 0.83 | SRD5A1 (0.49) | SRD5A1HRH3ADRB2NAMPTPOLB | |
| Hydrochloric Acid SCHEMBL2776093 | 0.82 | DPP4 (0.48) | SRD5A1HRH3ADRB2NAMPTEPHX2 | |
| Hydrochloric Acid SCHEMBL2775588 | 0.82 | DPP4 (0.48) | SRD5A1HRH3ADRB2NAMPTEPHX2 | |
| Hydrochloric Acid SCHEMBL2777270 | 0.82 | HRH3 (0.49) | SRD5A1HRH3ADRB2NAMPTPOLB | |
| SCHEMBL2777487 | 0.81 | HSD11B1 (0.59) | POLB | |
| Hydrochloric Acid SCHEMBL2774192 | 0.79 | DPP4 (0.49) | SRD5A1HRH3ADRB2NAMPTEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2258697-A1 | HYDROXYQUINOXALINECARBOXAMIDE DERIVATIVE | Daiichi Sankyo Company, Limited (JP) | 2010-12-08 | — | — | EP | disclosed |