Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.57 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.57 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.57 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.51 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28226601 | 0.86 | ADRB2 (0.61) | ADRB2ADRB1ADRB3ALOX5LPAR1 | |
| SCHEMBL9574183 | 0.86 | SMN1; SMN2 (0.44) | TDP1SMN1; SMN2HPGDKMT2AALDH1A1 | |
| SCHEMBL28191333 | 0.84 | MAPT (0.55) | TDP1KMT2AALDH1A1LMNA | |
| SCHEMBL31657295 | 0.82 | ADRB2 (0.57) | ADRB2ADRB1ADRB3ALOX5LPAR1 | |
| SCHEMBL28378702 | 0.82 | TLR2 (0.43) | ADRB2ADRB1ADRB3LPAR1TDP1 | |
| SCHEMBL28384042 | 0.82 | MAPT (0.58) | KMT2AALDH1A1LMNA | |
| SCHEMBL28886779 | 0.82 | MAPT (0.58) | KMT2AALDH1A1LMNA | |
| SCHEMBL28378432 | 0.82 | MAPT (0.58) | KMT2AALDH1A1LMNA | |
| SCHEMBL19024934 | 0.82 | ADRB2 (0.57) | ADRB2ADRB1ADRB3ALOX5LPAR1 | |
| SCHEMBL28377436 | 0.82 | MAPT (0.58) | KMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101489555-A | Nf-kappa | OTSUKA PHARMA CO LTD (JP) | 2009-07-22 | — | — | CN | disclosed |