Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27771257 | 0.87 | HDAC3 (0.34) | HTR6 | |
| SCHEMBL27750201 | 0.81 | HTR6 (0.39) | HTR6KMT2ACYP3A4CYP2D6 | |
| SCHEMBL28777651 | 0.80 | HTR6 (0.34) | HTR6CYP3A4CYP2D6 | |
| SCHEMBL27750242 | 0.78 | HTR6 (0.35) | HTR6 | |
| SCHEMBL27771191 | 0.78 | HTR6 (0.53) | HTR6CYP3A4CYP2D6 | |
| SCHEMBL3610149 | 0.73 | HTR6 (0.51) | HTR6 | |
| SCHEMBL27771123 | 0.72 | HTR6 (0.39) | HTR6CYP3A4CYP2D6 | |
| SCHEMBL27723333 | 0.71 | — | — | |
| SCHEMBL28781859 | 0.69 | HTR6 (0.52) | HTR6 | |
| SCHEMBL27771126 | 0.69 | CYP2D6 (0.36) | MEN1KMT2ACYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101484420-A | Indoles as 5-HT 6 modulators | BIOVITRUM AB PUBL (SE) | 2009-07-15 | — | — | CN | disclosed |