Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 20/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27771220 | 0.89 | HTR6 (0.58) | HTR6CYP3A4CYP2D6 | |
| SCHEMBL27750247 | 0.87 | HTR6 (0.56) | HTR6CYP3A4CYP2D6 | |
| SCHEMBL27771121 | 0.80 | HTR6 (0.42) | HTR6CYP3A4CYP2D6 | |
| SCHEMBL27750251 | 0.80 | HTR6 (0.42) | HTR6CYP3A4CYP2D6 | |
| Fluorobenzene SCHEMBL27760583 | 0.77 | HTR6 (0.66) | HTR6CYP3A4CYP2D6 | |
| Chlorobenzene SCHEMBL27782289 | 0.77 | HTR6 (0.63) | HTR6CYP3A4CYP2D6 | |
| Anisole SCHEMBL27782300 | 0.76 | HTR6 (0.67) | HTR6CYP3A4CYP2D6 | |
| SCHEMBL27771239 | 0.76 | HTR6 (0.56) | HTR6CYP3A4CYP2D6 | |
| SCHEMBL27760513 | 0.75 | HTR6 (0.69) | HTR6CYP3A4CYP2D6 | |
| SCHEMBL27760514 | 0.75 | HTR6 (0.63) | HTR6CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101484420-A | Indoles as 5-HT 6 modulators | BIOVITRUM AB PUBL (SE) | 2009-07-15 | — | — | CN | disclosed |