Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 10/20 | 0.59 |
| ▸ | RAB9A | P51151 | 5/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 3/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | SCD | O00767 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14757228 | 0.83 | GCK (0.74) | GCKRAB9ANPC1HPGDMEN1 | |
| SCHEMBL27771238 | 0.79 | MAOB (0.54) | RAB9ANPC1ALDH1A1KDM4ETP53 | |
| SCHEMBL27792358 | 0.79 | NPC1 (0.59) | RAB9ANPC1ALDH1A1TP53GAA | |
| SCHEMBL14757232 | 0.77 | NPC1 (0.78) | GCKRAB9ANPC1ALDH1A1HPGD | |
| SCHEMBL12974336 | 0.77 | MAOB (0.47) | GCKRAB9ANPC1ALDH1A1HPGD | |
| SCHEMBL2698147 | 0.76 | MAOB (0.46) | GCKRAB9ANPC1ALDH1A1HPGD | |
| SCHEMBL28781721 | 0.76 | NPC1 (0.71) | GCKRAB9ANPC1ALDH1A1HPGD | |
| SCHEMBL14757305 | 0.75 | GCK (0.73) | GCKRAB9ANPC1HPGDMEN1 | |
| SCHEMBL14757279 | 0.75 | GCK (0.71) | GCKRAB9ANPC1HPGDMEN1 | |
| SCHEMBL14757302 | 0.74 | GCK (0.71) | GCKRAB9ANPC1HPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101648919-A | 3-substituted salicylamide compound, preparation method, medicinal composition and application thereof | INST MATERIA MEDICA CAMS | 2010-02-17 | — | — | CN | claimed |
| CN-101648919-A | 3-substituted salicylamide compound, preparation method, medicinal composition and application thereof | INST MATERIA MEDICA CAMS | 2010-02-17 | — | — | CN | disclosed |