Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 8/20 | 0.54 |
| ▸ | MAOA | P21397 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 5/20 | 0.49 |
| ▸ | RAB9A | P51151 | 5/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | MITF | O75030 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.45 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.44 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27792358 | 0.84 | NPC1 (0.59) | MAOBMAOANPC1RAB9ATP53 | |
| SCHEMBL27771271 | 0.79 | GCK (0.59) | MAOBMAOANPC1RAB9AL3MBTL1 | |
| SCHEMBL12398726 | 0.78 | CXCR2 (0.67) | NPC1RAB9AL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL27792363 | 0.76 | RAB9A (0.57) | NPC1RAB9ATP53GAAKDM4E | |
| SCHEMBL27771260 | 0.75 | FADS1 (0.52) | MAOBMAOANPC1RAB9AKDM4E | |
| SCHEMBL27771246 | 0.73 | FADS1 (0.57) | MAOBMAOANPC1RAB9ATP53 | |
| SCHEMBL27792361 | 0.73 | KCNMA1 (0.66) | MAOBMAOANPC1RAB9AGAA | |
| SCHEMBL14758512 | 0.72 | RAB9A (0.71) | NPC1RAB9AL3MBTL1TP53GAA | |
| SCHEMBL27771262 | 0.71 | RAB9A (0.45) | NPC1RAB9AL3MBTL1TP53GAA | |
| SCHEMBL27771290 | 0.71 | NPC1 (0.64) | NPC1RAB9AL3MBTL1TP53GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101648919-A | 3-substituted salicylamide compound, preparation method, medicinal composition and application thereof | INST MATERIA MEDICA CAMS | 2010-02-17 | — | — | CN | claimed |
| CN-101648919-A | 3-substituted salicylamide compound, preparation method, medicinal composition and application thereof | INST MATERIA MEDICA CAMS | 2010-02-17 | — | — | CN | disclosed |