Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 6/20 | 0.32 |
| ▸ | CDK2 | P24941 | 6/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 3/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.31 |
| ▸ | CDK9 | P50750 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4102568 | 0.86 | DPP4 (0.40) | DPP4CCNE1CDK2GSK3B | |
| SCHEMBL27821593 | 0.86 | THRB (0.34) | GBA1DPP4CCNE1CDK2GSK3B | |
| SCHEMBL13774735 | 0.86 | DPP4 (0.40) | DPP4CCNE1CDK2GSK3B | |
| SCHEMBL28348910 | 0.83 | THRB (0.42) | GBA1DPP4TSHRMAPK1CCNE1 | |
| SCHEMBL27698362 | 0.83 | THRB (0.42) | GBA1DPP4TSHRMAPK1CCNE1 | |
| SCHEMBL28457660 | 0.82 | EPHX1 (0.38) | GBA1DPP4TSHRSMN1; SMN2 | |
| SCHEMBL25277512 | 0.81 | EPHX1 (0.36) | DPP4CCNE1CDK2GSK3BSMN1; SMN2 | |
| SCHEMBL28112921 | 0.80 | DPP4 (0.34) | DPP4MAPK1CCNE1CDK2GSK3B | |
| SCHEMBL7815595 | 0.79 | EPHX1 (0.42) | DPP4CCNE1CDK2GSK3BSMN1; SMN2 | |
| SCHEMBL28791460 | 0.79 | FABP7 (0.43) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111848423-B | Preparation method of tert-butyl 3-oxocyclobutylcarbamate | 尚科生物医药（上海）有限公司 | 2022-10-14 | — | — | CN | disclosed |
| CN-109305976-B | Compounds as ACC inhibitors and uses thereof | 南京圣和药业股份有限公司 | 2022-07-01 | — | — | CN | disclosed |
| CN-110959007-B | Compounds as ACC inhibitors and uses thereof | 南京圣和药业股份有限公司 | 2022-07-01 | — | — | CN | disclosed |
| CN-111670187-B | Beta-lactamase inhibitor and use thereof | 苏州信诺维医药科技有限公司 | 2021-04-16 | — | — | CN | disclosed |
| CN-111848423-A | Preparation method of tert-butyl 3-oxocyclobutylcarbamate | 尚科生物医药（上海）有限公司 | 2020-10-30 | — | — | CN | disclosed |
| CN-111670187-A | Beta-lactamase inhibitor and use thereof | 苏州信诺维医药科技有限公司 | 2020-09-15 | — | — | CN | disclosed |
| CN-110959007-A | Compounds as ACC inhibitors and uses thereof | 南京圣和药业股份有限公司 | 2020-04-03 | — | — | CN | disclosed |
| CN-110194770-A | Peptide acyl arginine deiminase inhibitor and application thereof | 南京药捷安康生物科技有限公司 | 2019-09-03 | — | — | CN | disclosed |
| CN-109305976-A | Compound and its application as ACC inhibitor | 南京圣和药业股份有限公司 | 2019-02-05 | — | — | CN | disclosed |
| CN-107529748-A | Molecule with desinsection effectiveness, and relative intermediate, composition and method | 美国陶氏益农公司 | 2018-01-02 | — | — | CN | disclosed |
| CN-106188027-A | Heteroaromatic analog derivative and the application in medicine thereof | 广东东阳光药业有限公司 | 2016-12-07 | — | — | CN | disclosed |
| CN-104136411-B | Therapeutically active compounds and methods of use thereof | 安吉奥斯医药品有限公司 | 2016-10-12 | — | — | CN | disclosed |
| CN-103635456-B | Tigecycline derivatives | KBP BIOSCIENCES Co.,Ltd. (CN) | 2016-03-09 | — | — | CN | disclosed |
| CN-103717571-B | The tetracycline compound that 9-amino methyl replaces | KBP BIOSCIENCES Co.,Ltd. (CN) | 2016-01-13 | — | — | CN | disclosed |
| CN-104487431-A | Novel indazoles for the treatment and prophylaxis of respiratory syncytial virus infection | HOFFMANN LA ROCHE | 2015-04-01 | — | — | CN | disclosed |
| CN-104334558-A | 1,3, 4-oxadiazole and 1,3, 4-thiadiazole beta-lactamase inhibitors | CUBIST PHARM INC | 2015-02-04 | — | — | CN | disclosed |
| CN-103814030-A | Pyrrolopyrimidine and purine derivatives | PFIZER | 2014-05-21 | — | — | CN | disclosed |
| CN-101595094-B | Cycloalkylamine substituted isoquinolone derivatives | SANOFI AVENTIS | 2013-02-20 | — | — | CN | disclosed |
| CN-102596963-A | Ether derivatives of bicyclic heteroaryls | NOVARTIS AG | 2012-07-18 | — | — | CN | disclosed |
| CN-101595094-A | The isoquinolone derivatives that Cycloalkyl amine replaces | SANOFI AVENTIS (FR) | 2009-12-02 | — | — | CN | disclosed |