Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | HRH2 | P25021 | 3/20 | 0.36 |
| ▸ | HRH1 | P35367 | 3/20 | 0.36 |
| ▸ | MYC | P01106 | 1/20 | 0.36 |
| ▸ | MAX | P61244 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CASP6 | P55212 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2782646 | 0.99 | EPHX2 (0.40) | EPHX2KDM4EHPGDGLAGAA | |
| SCHEMBL2778319 | 0.86 | ALDH1A1 (0.42) | EPHX2KDM4EHPGDGLAGAA | |
| SCHEMBL2778886 | 0.86 | ALDH1A1 (0.42) | EPHX2KDM4EHPGDGLAGAA | |
| SCHEMBL13086369 | 0.86 | EPHX2 (0.40) | EPHX2KDM4EHPGDGLAGAA | |
| SCHEMBL13086405 | 0.85 | EPHX2 (0.41) | EPHX2KDM4EHPGDGLAGAA | |
| SCHEMBL2781215 | 0.84 | ALDH1A1 (0.40) | KDM4EHPGDGLAGAAMAPT | |
| SCHEMBL2777905 | 0.83 | ALDH1A1 (0.41) | KDM4EHPGDGLAGAAMAPT | |
| SCHEMBL2777282 | 0.81 | EPHX2 (0.39) | EPHX2KDM4EHPGDGLAGAA | |
| SCHEMBL2782649 | 0.80 | EPHX2 (0.38) | EPHX2KDM4EHPGDGLAGAA | |
| SCHEMBL13085814 | 0.72 | EPHX2 (0.39) | EPHX2KDM4EHPGDGLAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010118968-A1 | NO-DONOR ASPIRIN DERIVATIVES | NICOX S.A. (FR) | 2010-10-21 | — | — | WO | disclosed |