Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 5/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CCR6 | P51684 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2791751 | 0.81 | PPARG (0.54) | ACACBPPARGPPARADRD1ALDH1A1 | |
| SCHEMBL2797770 | 0.80 | ACACB (0.51) | ACACBPPARGPPARADRD1ALDH1A1 | |
| SCHEMBL163916 | 0.79 | DRD1 (0.37) | DRD1ALDH1A1MEN1KMT2AALOX15 | |
| SCHEMBL28019240 | 0.75 | APP (0.37) | FFAR1MAPTAPP | |
| SCHEMBL2188836 | 0.74 | APP (0.57) | ALDH1A1MEN1KMT2AALOX15FFAR1 | |
| SCHEMBL5496752 | 0.73 | TSHR (0.46) | ALDH1A1FFAR1MAPTAPP | |
| SCHEMBL9060995 | 0.72 | ACACB (0.49) | ACACBPPARGPPARADRD1ALDH1A1 | |
| SCHEMBL4268626 | 0.72 | APP (0.37) | MAPTAPP | |
| SCHEMBL5495027 | 0.72 | APP (0.47) | ALDH1A1MEN1KMT2AALOX15FFAR1 | |
| SCHEMBL5492434 | 0.72 | MAPT (0.59) | ALDH1A1MEN1KMT2AFFAR1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101663281-A | Amino-5- [ 4- (difluoromethoxy) phenyl ] -5-phenylimidazolidinone compounds which inhibit the beta-secretase enzyme | WYETH CORP | 2010-03-03 | — | — | CN | disclosed |