Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.37 |
| ▸ | GRM5 | P41594 | 6/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP12 | P39900 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2188836 | 0.83 | APP (0.57) | APPGRM5FFAR1MAPTCA12 | |
| SCHEMBL5496752 | 0.82 | TSHR (0.46) | APPFFAR1MAPTCA12CA1 | |
| SCHEMBL2539548 | 0.80 | APP (0.37) | APPGRM5MAPT | |
| SCHEMBL2545694 | 0.80 | APP (0.37) | APPMAPT | |
| SCHEMBL4268626 | 0.80 | APP (0.37) | APPMAPT | |
| SCHEMBL5492434 | 0.80 | MAPT (0.59) | APPFFAR1MAPTCA12CA1 | |
| SCHEMBL5495027 | 0.80 | APP (0.47) | APPFFAR1MAPTCA12CA1 | |
| SCHEMBL5493305 | 0.76 | APP (0.33) | APPMAPT | |
| SCHEMBL27809063 | 0.76 | ALDH1A1 (0.39) | APPGRM5MAPT | |
| SCHEMBL5492278 | 0.76 | APP (0.33) | APPMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104710304-A | Preparation method of 1-benzylidene-2-alkenyl-3-indene ester series compounds | UNIV JIANGXI NORMAL | 2015-06-17 | — | — | CN | disclosed |