SCHEMBL2777451

SCHEMBL2777451

Oc1ccc(C2(c3ccc(O)cc3)CCc3ccccc32)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 3/20 0.41
MAOB P27338 1/20 0.41
HDAC9 Q9UKV0 1/20 0.41
ESR1 P03372 3/20 0.39
ESR2 Q92731 3/20 0.39
TSHR P16473 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
CHRM2 P08172 1/20 0.38
ADORA3 P0DMS8 1/20 0.38
KCNH2 Q12809 1/20 0.38
ALDH1A1 P00352 1/20 0.38
LMNA P02545 1/20 0.38
TP53 P04637 1/20 0.38
TYMS P04818 1/20 0.38
CYP3A4 P08684 1/20 0.38
MAPT P10636 1/20 0.38
ALOX15 P16050 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9284139 0.91 KDM1A (0.44) KDM1AESR1ESR2MEN1KMT2A
SCHEMBL6337745 0.84 HDAC9 (0.49) KDM1AMAOBHDAC9TSHRTDP1
SCHEMBL6552454 0.81 KDM1A (0.44) KDM1AMAOBHDAC9TSHRTDP1
SCHEMBL7885283 0.80 BRD4 (0.40) KDM1AMAOBHDAC9ESR1ESR2
SCHEMBL7457135 0.79 KDM1A (0.42) KDM1AMAOBHDAC9ESR1ESR2
SCHEMBL15518954 0.79 KDM1A (0.44) KDM1AMAOBHDAC9TSHRTDP1
SCHEMBL13668294 0.78 AKR1B1 (0.50) HDAC9TDP1KMT2AALDH1A1LMNA
SCHEMBL9068200 0.78 BCL2L1 (0.36) HDAC9ESR1ESR2TSHRTDP1
SCHEMBL5687667 0.78 KDM1A (0.50) KDM1AMAOBHDAC9TSHRTDP1
SCHEMBL14701153 0.77 SIGMAR1 (0.50) MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4786668-A POLYETHER EPOXIDE THERMOPLASTIC FIBER REINFORCED COMPOSITES FOR AEROSPACE APPLICATIONS SHELL OIL COMPANY (US) 1988-11-22 US claimed
WO-2024157820-A1 RESIN SHEET 味の素株式会社 2024-08-02 WO disclosed
WO-2020162403-A1 POLYMER, POLYMERIZABLE COMPOSITION AND CURED PRODUCT 株式会社ADEKA 2020-08-13 WO disclosed
US-9777184-B2 (Meth)acrylic resin composition, film, polarizing plate protective film, polarizing plate, and liquid crystal display device FUJIFILM CORPORATION (JP) 2017-10-03 US disclosed
US-9777184-B2 (Meth)acrylic resin composition, film, polarizing plate protective film, polarizing plate, and liquid crystal display device FUJIFILM CORPORATION (JP) 2017-10-03 US disclosed
US-9715040-B2 Optical film and manufacturing method thereof, polarizing plate protective film, polarizing plate and liquid crystal display device FUJIFILM CORPORATION (JP) 2017-07-25 US disclosed
US-9715040-B2 Optical film and manufacturing method thereof, polarizing plate protective film, polarizing plate and liquid crystal display device FUJIFILM CORPORATION (JP) 2017-07-25 US disclosed
US-9715041-B2 Optical film, polarizing plate protective film, polarizing plate and liquid crystal display device FUJIFILM CORPORATION (JP) 2017-07-25 US disclosed
US-9715041-B2 Optical film, polarizing plate protective film, polarizing plate and liquid crystal display device FUJIFILM CORPORATION (JP) 2017-07-25 US disclosed
EP-2892868-B1 INDANE BISPHENOLS, POLYMERS DERIVED THEREFROM, AND METHODS OF USE THEREOF SABIC GLOBAL TECHNOLOGIES BV (NL) 2017-01-11 EP disclosed
US-20100015551-A1 NOVEL EPOXY COMPOUND, ALKALI-DEVELOPABLE RESIN COMPOSITION, AND ALKALI-DEVELOPABLE PHOTOSENSITIVE RESIN COMPOSITION ADEKA CORPORATION (JP) 2010-01-21 US disclosed
EP-2145880-A1 NOVEL EPOXY COMPOUND, ALKALI-DEVELOPABLE RESIN COMPOSITION, AND ALKALI-DEVELOPABLE PHOTOSENSITIVE RESIN COMPOSITION Adeka Corporation (JP) 2010-01-20 EP disclosed
EP-2145880-A1 NOVEL EPOXY COMPOUND, ALKALI-DEVELOPABLE RESIN COMPOSITION, AND ALKALI-DEVELOPABLE PHOTOSENSITIVE RESIN COMPOSITION Adeka Corporation (JP) 2010-01-20 EP disclosed
EP-1047411-B1 SUBSTITUTED DIPHENYL INDANONE, INDANE AND INDOLE COMPOUNDS AND ANALOGUES THEREOF USEFUL FOR THE TREATMENT OR PREVENTION OF DISEASES CHARACTERIZED BY ABNORMAL CELL PROLIFERATION HARVARD COLLEGE (US) 2004-02-11 EP disclosed
US-4861810-A DIEPOXIDES, MODULUS, TOUGHNESS, GLASS TRANSITION TEMPERATURE SHELL OIL COMPANY (US) 1989-08-29 US disclosed
US-4786669-A POLYETHER EPOXIDE THERMOSETTING FIBER REINFORCED COMPOSITES FOR AUTOMOTIVE APPLICATIONS SHELL OIL COMPANY (US) 1988-11-22 US disclosed
US-4786668-A POLYETHER EPOXIDE THERMOPLASTIC FIBER REINFORCED COMPOSITES FOR AEROSPACE APPLICATIONS SHELL OIL COMPANY (US) 1988-11-22 US disclosed
EP-0249263-A2 Thermoplastic polymer composition having thermosetting processing characteristics SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1987-12-16 EP disclosed
EP-0249262-A2 Thermoplastic polymer composition having thermosetting processing characteristics SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1987-12-16 EP disclosed
US-4221895-A POLYESTER, POLYSULFONATE, OR POLYSULFINATE THE DOW CHEMICAL COMPANY (US) 1980-09-09 US disclosed