Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 2/20 | 0.50 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL290754 | 1.00 | HDAC4 (0.50) | HDAC4AKR1C1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL1953126 | 0.98 | AKR1C1 (0.50) | HDAC4AKR1C1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL1612406 | 0.82 | HDAC4 (0.47) | HDAC4AKR1C1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL13222778 | 0.80 | SLC6A2 (0.49) | HDAC4AKR1C1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL27296884 | 0.80 | HDAC4 (0.46) | HDAC4AKR1C1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL290573 | 0.79 | OPRM1 (0.46) | HDAC4SLC6A2SLC6A4SLC6A3MEN1 | |
| SCHEMBL14899045 | 0.78 | AKR1C1 (0.48) | HDAC4AKR1C1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8655542 | 0.77 | SLC6A4 (0.54) | HDAC4AKR1C1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL28776197 | 0.76 | SLC6A4 (0.50) | HDAC4AKR1C1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6669439 | 0.76 | HDAC4 (0.49) | HDAC4AKR1C1SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101663263-A | Solid forms comprising (-) -O-desmethylvenlafaxine and uses thereof | SEPRACOR INC | 2010-03-03 | — | — | CN | disclosed |