Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 11/20 | 0.44 |
| ▸ | PI4K2B | Q8TCG2 | 11/20 | 0.44 |
| ▸ | PI4K2A | Q9BTU6 | 11/20 | 0.44 |
| ▸ | PI4KB | Q9UBF8 | 11/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 12/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 8/20 | 0.44 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5039983 | 0.72 | PI4KA (0.56) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL4439065 | 0.72 | PI4KA (0.53) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL258584 | 0.72 | ADORA2A (0.59) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL27774795 | 0.71 | HSP90AA1 (0.52) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL16487121 | 0.67 | PI4KA (0.51) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL580610 | 0.65 | ADORA2A (0.64) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL11457654 | 0.65 | ADORA2A (0.55) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL2020952 | 0.65 | PI4KA (0.59) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| Hydrochloric Acid SCHEMBL1895413 | 0.64 | PI4KA (0.57) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL28413958 | 0.63 | ADORA2A (0.62) | PI4KAPI4K2BPI4K2API4KBADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101505762-A | Orally active purinyl inhibitors of heat shock protein 90 | CONFORMA THERAPEUTICS CORP (US) | 2009-08-12 | — | — | CN | disclosed |