SCHEMBL258584

SCHEMBL258584

CSn1cnc2c(N)ncnc21

nearest known ligand 0.59

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ADORA2A P29274 11/20 0.59
ADORA1 P30542 9/20 0.59
PI4KA P42356 10/20 0.54
PI4K2B Q8TCG2 10/20 0.54
PI4K2A Q9BTU6 10/20 0.54
PI4KB Q9UBF8 10/20 0.54
ADORA2B P29275 4/20 0.54
GSK3B P49841 1/20 0.47
EGFR P00533 1/20 0.47
AHCY P23526 1/20 0.46
ADORA3 P0DMS8 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5039983 0.75 PI4KA (0.56) ADORA2AADORA1PI4KAPI4K2BPI4K2A
SCHEMBL5144936 0.75 ADORA2A (0.57) ADORA2AADORA1PI4KAPI4K2BPI4K2A
SCHEMBL106573 0.75 ADORA2A (1.00) ADORA2AADORA1PI4KAPI4K2BPI4K2A
SCHEMBL580610 0.74 ADORA2A (0.64) ADORA2AADORA1PI4KAPI4K2BPI4K2A
SCHEMBL11457654 0.74 ADORA2A (0.55) ADORA2AADORA1PI4KAPI4K2BPI4K2A
SCHEMBL7140260 0.73 ADORA2A (0.96) ADORA2AADORA1PI4KAPI4K2BPI4K2A
SCHEMBL667204 0.72 ADORA2A (0.62) ADORA2AADORA1PI4KAPI4K2BPI4K2A
SCHEMBL28413958 0.72 ADORA2A (0.62) ADORA2AADORA1PI4KAPI4K2BPI4K2A
SCHEMBL6883849 0.72 ADORA2A (0.61) ADORA2AADORA1PI4KAPI4K2BPI4K2A
SCHEMBL27774840 0.72 PI4KA (0.44) ADORA2AADORA1PI4KAPI4K2BPI4K2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 815 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0805690-B1 METHOD FOR SELECTIVE METHIONINE STARVATION OF MALIGNANT CELLS IN MAMMALS UNIV CALIFORNIA (US) 2002-08-07 EP claimed
US-20260024621-A1 OLIGONUCLEOTIDE-BASED MACHINE LEARNING CREYON BIO INC (US) 2026-01-22 US disclosed
US-12527877-B2 Anti-transferrin receptor antibodies, conjugates thereof, and uses thereof Arrowhead Pharmaceuticals, Inc. (US) 2026-01-20 US disclosed
US-12472199-B2 P-ethoxy nucleic acids for IGF-1R inhibition THOMAS JEFFERSON UNIVERSITY (US) 2025-11-18 US disclosed
US-12400739-B2 Oligonucleotide-based machine learning CREYON BIO, INC. (US) 2025-08-26 US disclosed
US-20250255897-A1 P-ETHOXY NUCLEIC ACIDS FOR LIPOSOMAL FORMULATION Bio-Path Holdings, Inc. (US) 2025-08-14 US disclosed
US-20250235549-A1 ANTI-TRANSFERRIN RECEPTOR ANTIBODIES, CONJUGATES THEREOF, AND USES THEREOF Arrowhead Pharmaceuticals, Inc. 2025-07-24 US disclosed
US-12319911-B2 P-ethoxy nucleic acids for STAT3 inhibition Bio-Path Holdings, Inc. (US) 2025-06-03 US disclosed
US-12234457-B2 P-ethoxy nucleic acids for BCL2 inhibition Bio-Path Holdings, Inc. (US) 2025-02-25 US disclosed
US-20240404636-A1 OLIGONUCLEOTIDE-BASED MACHINE LEARNING CREYON BIO, INC. 2024-12-05 US disclosed
EP-0789577-A4 SYNTHESIS OF N-SUBSTITUTED OLIGOMERS CHIRON CORP (US) 1998-07-22 EP disclosed
EP-0800526-A1 METHOD FOR THE CONTROLLED SYNTHESIS OF POLYNUCLEOTIDE MIXTURES WHICH ENCODE DESIRED MIXTURES OF PEPTIDES CHIRON CORPORATION (US) 1997-10-15 EP disclosed
EP-0789577-A1 SYNTHESIS OF N-SUBSTITUTED OLIGOMERS CHIRON CORPORATION (US) 1997-08-20 EP disclosed
EP-0777492-A1 COMBINATORIAL LIBRARIES OF SUBSTRATE-BOUND CYCLIC ORGANIC COMPOUNDS CHIRON CORPORATION (US) 1997-06-11 EP disclosed
EP-0671928-A4 SYNTHESIS OF N-SUBSTITUTED OLIGOMERS. CHIRON CORP (US) 1997-04-23 EP disclosed
WO-1996040202-A1 SYNTHESIS OF N-SUBSTITUTED OLIGOMERS CHIRON CORPORATION (US) 1996-12-19 WO disclosed
WO-1996040201-A1 COMBINATORIAL LIBRARIES OF SUBSTRATE-BOUND CYCLIC ORGANIC COMPOUNDS CHIRON CORPORATION (US) 1996-12-19 WO disclosed
WO-1996020947-A1 METHOD FOR THE CONTROLLED SYNTHESIS OF POLYNUCLEOTIDE MIXTURES WHICH ENCODE DESIRED MIXTURES OF PEPTIDES CHIRON CORPORATION (US) 1996-07-11 WO disclosed
EP-0671928-A1 SYNTHESIS OF N-SUBSTITUTED OLIGOMERS CHIRON CORPORATION (US) 1995-09-20 EP disclosed
WO-1994006451-A1 SYNTHESIS OF N-SUBSTITUTED OLIGOMERS CHIRON CORPORATION (US) 1994-03-31 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260024621-A1 OLIGONUCLEOTIDE-BASED MACHINE LEARNING POLN, TOP1, NCL ADORA2A 3374/4885ADORA1 1013/4885PI4KA 2368/4885
US-12527877-B2 Anti-transferrin receptor antibodies, conjugates thereof, and uses thereof MUSK, TFRC, FTH1 ADORA2A 4103/4885ADORA1 3680/4885PI4KA 3765/4885
US-20250235549-A1 ANTI-TRANSFERRIN RECEPTOR ANTIBODIES, CONJUGATES THEREOF, AND USES THEREOF TFRC, MUSK, FOLR1 ADORA2A 2102/4885ADORA1 840/4885PI4KA 4248/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.