Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | MIF | P14174 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27456541 | 0.85 | ATM (0.46) | ATML3MBTL1CYP1A2ELANEMAPT | |
| SCHEMBL766470 | 0.83 | ATM (0.45) | ATML3MBTL1CYP1A2ELANEMAPT | |
| SCHEMBL27617143 | 0.79 | ALDH1A1 (0.51) | L3MBTL1NPC1HPGDRAB9ATDP1 | |
| SCHEMBL27517147 | 0.79 | ALDH1A1 (0.51) | L3MBTL1NPC1HPGDRAB9ATDP1 | |
| Hydrochloric Acid SCHEMBL27758297 | 0.78 | ALDH1A1 (0.50) | L3MBTL1HPGDTDP1ALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL27712313 | 0.78 | ALDH1A1 (0.50) | L3MBTL1HPGDTDP1ALDH1A1KMT2A | |
| SCHEMBL650209 | 0.77 | ATM (0.51) | ATML3MBTL1CYP1A2ELANEMAPT | |
| SCHEMBL19105214 | 0.77 | ATM (0.51) | ATML3MBTL1CYP1A2ELANEMAPT | |
| SCHEMBL1645806 | 0.76 | ATM (0.47) | ATML3MBTL1CYP1A2ELANEMAPT | |
| SCHEMBL14996055 | 0.75 | ELANE (0.50) | ATML3MBTL1CYP1A2ELANEMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101663293-B | Quinoline-carboxamide derivatives as p2y12 antagonists | SANOFI AVENTIS SPA | 2013-07-31 | — | — | CN | disclosed |
| CN-101663293-A | Quinoline-carboxamide derivatives as p2y12 antagonists | SANOFI AVENTIS | 2010-03-03 | — | — | CN | disclosed |