SCHEMBL27775652

SCHEMBL27775652

O=C1N[C@H]2[C@H](CS[C@H]2CCCCC(=O)OS)N1

nearest known ligand 0.77

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ TDP1 Q9NUW8 6/20 0.77
▸ MEN1 O00255 1/20 0.71
▸ ABL1 P00519 1/20 0.71
▸ LMNA P02545 1/20 0.71
▸ PKM P14618 1/20 0.71
▸ IDE P14735 1/20 0.71
▸ MAPK1 P28482 1/20 0.71
▸ KMT2A Q03164 1/20 0.71
▸ RIN1 Q13671 1/20 0.71
▸ L3MBTL1 Q9Y468 1/20 0.71
▸ HLCS P50747 6/20 0.63
▸ CA12 O43570 5/20 0.52
▸ CA1 P00915 5/20 0.52
▸ CA2 P00918 5/20 0.52
▸ CA9 Q16790 5/20 0.52
▸ HPSE Q9Y251 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29994754 1.00 TDP1 (0.77) TDP1MEN1ABL1LMNAPKM
SCHEMBL22290232 0.91 TDP1 (0.82) TDP1MEN1ABL1LMNAPKM
SCHEMBL21114407 0.89 TDP1 (0.81) TDP1MEN1ABL1LMNAPKM
SCHEMBL28119479 0.89 TDP1 (0.81) TDP1MEN1ABL1LMNAPKM
SCHEMBL21176811 0.89 TDP1 (0.81) TDP1MEN1ABL1LMNAPKM
SCHEMBL28283183 0.89 TDP1 (0.81) TDP1MEN1ABL1LMNAPKM
SCHEMBL22265330 0.88 TDP1 (0.79) TDP1MEN1ABL1LMNAPKM
SCHEMBL23065674 0.87 TDP1 (0.77) TDP1MEN1ABL1LMNAPKM
SCHEMBL7109641 0.87 TDP1 (0.81) TDP1MEN1ABL1LMNAPKM
SCHEMBL10047674 0.87 TDP1 (1.00) TDP1MEN1ABL1LMNAPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113980089-B Method for detecting cell outer membrane vesicles in sample and application of detection kit 富士胶片株式会社 2024-12-27 — — CN disclosed
CN-113980089-A Method for detecting outer membrane vesicles in sample and application of detection kit 富士胶片和光纯药株式会社 2022-01-28 — — CN disclosed
CN-111269164-B Ketone compound, preparation method and application thereof, and method for site-directed modification of protein containing cysteine residues or disulfide bonds 南开大学 2021-11-02 — — CN disclosed
CN-111269164-A Ketone compound, preparation method and application thereof, and method for site-directed modification of protein containing cysteine residues or disulfide bonds 南开大学 2020-06-12 — — CN disclosed
CN-105181658-B Sensing device, sensing system using same and sensing method 中央研究院 2018-11-23 — — CN disclosed
CN-104001181-B Selected antibody binding to anionic phospholipids and amino phosphatidic and treating and diagnosing application thereof 得克萨斯大学体系董事会 2017-05-10 — — CN disclosed
CN-104225610-B The selected antibodies being combined with anionic phospholipid and aminophospholipids and its therapeutic use 得克萨斯大学体系董事会 2017-03-01 — — CN disclosed
CN-105181658-A Sensing device, sensing system using same and sensing method ACADEMIA SINICA 2015-12-23 — — CN disclosed
CN-104225610-A Selected antibody compositions for binding to aminophospholipids and therapeutic use thereof UNIV TEXAS 2014-12-24 — — CN disclosed
CN-104001181-A Peptides binding to phosphatidylethanolamine and their use in treating viral infections and cancer UNIV TEXAS 2014-08-27 — — CN disclosed
CN-101653603-B Peptides and antibodies binding to anionic phospholipids and aminophospholipids and their use in treating disease UNIV TEXAS 2014-07-09 — — CN disclosed
CN-103649718-A Method for generating metamaterial and metamaterial generated thereby UNIV NANYANG TECH 2014-03-19 — — CN disclosed
CN-101653603-A Peptides and antibodies binding to anionic phospholipids and aminophospholipids and their use in treating disease UNIV TEXAS US 2010-02-24 — — CN disclosed
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