Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.77 |
| ▸ | MEN1 | O00255 | 1/20 | 0.71 |
| ▸ | ABL1 | P00519 | 1/20 | 0.71 |
| ▸ | LMNA | P02545 | 1/20 | 0.71 |
| ▸ | PKM | P14618 | 1/20 | 0.71 |
| ▸ | IDE | P14735 | 1/20 | 0.71 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.71 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.71 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.71 |
| ▸ | HLCS | P50747 | 6/20 | 0.63 |
| ▸ | CA12 | O43570 | 5/20 | 0.52 |
| ▸ | CA1 | P00915 | 5/20 | 0.52 |
| ▸ | CA2 | P00918 | 5/20 | 0.52 |
| ▸ | CA9 | Q16790 | 5/20 | 0.52 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27775652 | 1.00 | TDP1 (0.77) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL22290232 | 0.91 | TDP1 (0.82) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL21114407 | 0.89 | TDP1 (0.81) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL28119479 | 0.89 | TDP1 (0.81) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL21176811 | 0.89 | TDP1 (0.81) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL28283183 | 0.89 | TDP1 (0.81) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL22265330 | 0.88 | TDP1 (0.79) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL23065674 | 0.87 | TDP1 (0.77) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL7109641 | 0.87 | TDP1 (0.81) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL10047674 | 0.87 | TDP1 (1.00) | TDP1MEN1ABL1LMNAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025217257-A1 | ENGINEERED CIRCULARIZED PEGRNAS AND USES THEREOF | TRUSTEES OF BOSTON UNIVERSITY (US) | 2025-10-16 | — | — | WO | disclosed |
| EP-4543481-A1 | ALPHA1-ANTITRYPSIN FOR USE IN THE TREATMENT OF DISEASES OR DISORDERS OF THE NERVOUS SYSTEM SUCH AS CHRONIC INFLAMMATORY DEMYELINATING POLYNEUROPATHY | Ageronix SA (CH) | 2025-04-30 | — | — | EP | disclosed |
| CN-119317441-A | Alpha 1-antitrypsin for the treatment of diseases or conditions of the nervous system such as chronic inflammatory demyelinating polyneuropathy | 阿格罗尼克斯股份有限公司 | 2025-01-14 | — | — | CN | disclosed |
| WO-2023247736-A1 | ALPHA1-ANTITRYPSIN FOR USE IN THE TREATMENT OF DISEASES OR DISORDERS OF THE NERVOUS SYSTEM SUCH AS CHRONIC INFLAMMATORY DEMYELINATING POLYNEUROPATHY | Ageronix SA (CH) | 2023-12-28 | — | — | WO | disclosed |
| EP-4069748-A1 | MODULATORS OF THE IMMUNE ESCAPE MECHANISM FOR UNIVERSAL CELL THERAPY | Vycellix, Inc. (US) | 2022-10-12 | — | — | EP | disclosed |