Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PTGES | O14684 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | KMO | O15229 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3510252 | 0.84 | KMO (0.49) | KMT2AMEN1POLBKMO | |
| SCHEMBL3350743 | 0.82 | NR1H2 (0.46) | SMN1; SMN2EGFR | |
| SCHEMBL2446897 | 0.80 | FGFR2 (0.41) | KMT2AMEN1PTGESKDM4ELMNA | |
| SCHEMBL2448153 | 0.75 | NR1H2 (0.40) | KMT2AMAPTMEN1KDM4EHPGD | |
| SCHEMBL2446322 | 0.73 | NR1H3 (0.46) | EGFR | |
| SCHEMBL3509660 | 0.73 | MAP4K4 (0.39) | EGFR | |
| SCHEMBL2449201 | 0.73 | FFAR4 (0.43) | — | |
| SCHEMBL27666473 | 0.73 | KMT2A (0.58) | KMT2AMAPTMEN1TDP1POLB | |
| SCHEMBL3507653 | 0.72 | EGFR (0.36) | EGFR | |
| SCHEMBL3507103 | 0.71 | NR1H2 (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101679311-A | Quinazoline compound | WYETH CORP | 2010-03-24 | — | — | CN | claimed |
| CN-101679311-A | Quinazoline compound | WYETH CORP | 2010-03-24 | — | — | CN | disclosed |