Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | CASP3 | P42574 | 2/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.49 |
| ▸ | NQO2 | P16083 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | APAF1 | O14727 | 1/20 | 0.42 |
| ▸ | CDC25B | P30305 | 1/20 | 0.42 |
| ▸ | CASP6 | P55212 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27775778 | 0.89 | NPC1 (0.53) | NPC1RAB9ACASP3SENP7NQO2 | |
| SCHEMBL4440686 | 0.88 | NPC1 (0.49) | NPC1RAB9ACASP3SENP7NQO2 | |
| SCHEMBL28785487 | 0.83 | NPC1 (0.49) | NPC1RAB9ACASP3SENP7NQO2 | |
| SCHEMBL28785477 | 0.81 | ABCB1 (0.50) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL27796823 | 0.79 | NTRK1 (0.62) | NPC1RAB9ACASP3SENP7MEN1 | |
| SCHEMBL27775774 | 0.79 | RXFP1 (0.56) | NPC1RAB9ACASP3SENP7NQO2 | |
| SCHEMBL27775945 | 0.77 | NPC1 (0.51) | NPC1RAB9ACASP3SENP7NQO2 | |
| SCHEMBL28785517 | 0.77 | MEN1 (0.55) | NPC1RAB9ACASP3SENP7NQO2 | |
| SCHEMBL2816734 | 0.77 | MAPT (0.62) | NPC1RAB9ACASP3SENP7NQO2 | |
| SCHEMBL27796913 | 0.77 | KDM4E (0.58) | NPC1RAB9ACASP3SENP7NQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101679215-A | New benzamide derivatives as the follicle stimulating hormone conditioning agent | ADDEX PHARMA SA | 2010-03-24 | — | — | CN | disclosed |