Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | NQO2 | P16083 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27775889 | 0.88 | NPC1 (0.49) | NPC1RAB9ANQO2CASP3SENP7 | |
| SCHEMBL4440418 | 0.83 | NPC1 (0.49) | NPC1RAB9ANQO2CASP3SENP7 | |
| SCHEMBL2816819 | 0.82 | MEN1 (0.63) | NPC1RAB9ANQO2CASP3SENP7 | |
| SCHEMBL2815122 | 0.80 | KMT2A (0.57) | NPC1RAB9ANQO2CASP3SENP7 | |
| SCHEMBL4446447 | 0.79 | PIN1 (0.56) | NPC1RAB9ANQO2CASP3SENP7 | |
| SCHEMBL2818006 | 0.79 | MEN1 (0.53) | NPC1RAB9ANQO2CASP3SENP7 | |
| SCHEMBL2816216 | 0.79 | ROCK2 (0.56) | NPC1RAB9ANQO2CASP3SENP7 | |
| SCHEMBL2815071 | 0.78 | MEN1 (0.54) | NPC1RAB9ANQO2CASP3SENP7 | |
| SCHEMBL4555728 | 0.78 | FLT3 (0.55) | NPC1MEN1KMT2ANR1H4SMN1; SMN2 | |
| SCHEMBL4556336 | 0.78 | NPC1 (0.58) | NPC1RAB9ANQO2CASP3SENP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2134676-A2 | NOVEL BENZAMIDE DERIVATIVES AS MODULATORS OF THE FOLLICLE STIMULATING HORMONE | Addex Pharma SA (CH) | 2009-12-23 | — | — | EP | disclosed |
| WO-2008117175-A2 | NOVEL BENZAMIDE DERIVATIVES AS MODULATORS OF THE FOLLICLE STIMULATING HORMONE | ADDEX PHARMA SA (CH) | 2008-10-02 | — | — | WO | disclosed |