Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNG2 | P59768 | 2/20 | 0.56 |
| ▸ | GNB1 | P62873 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | MMP1 | P03956 | 1/20 | 0.56 |
| ▸ | MMP9 | P14780 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | NCF1 | P14598 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | CASP7 | P55210 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.45 |
| ▸ | TERT | O14746 | 2/20 | 0.45 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11307337 | 0.99 | GNG2 (0.55) | GNG2GNB1MEN1MMP1MMP9 | |
| SCHEMBL2779314 | 0.84 | GNG2 (0.49) | GNG2GNB1MEN1MMP1MMP9 | |
| SCHEMBL2775377 | 0.83 | GNG2 (0.48) | GNG2GNB1MEN1MMP1MMP9 | |
| SCHEMBL2780312 | 0.82 | GNG2 (0.47) | GNG2GNB1MEN1MMP1MMP9 | |
| SCHEMBL3238508 | 0.75 | GNG2 (0.61) | GNG2GNB1MEN1MMP1MMP9 | |
| SCHEMBL807331 | 0.75 | GNG2 (0.68) | GNG2GNB1MEN1MMP1MMP9 | |
| SCHEMBL8359605 | 0.75 | GNG2 (0.83) | GNG2GNB1MEN1MMP1MMP9 | |
| Hydrochloric Acid SCHEMBL31428470 | 0.74 | GNG2 (0.60) | GNG2GNB1MEN1MMP1MMP9 | |
| SCHEMBL28854429 | 0.73 | GNG2 (0.81) | GNG2GNB1MEN1MMP1MMP9 | |
| Aminoquinuride SCHEMBL14690740 | 0.72 | GNG2 (0.94) | GNG2GNB1MEN1MMP1MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2147310-A2 | COMPOSITIONS AND METHODS FOR INHIBITING G PROTEIN SIGNALING | University of Rochester (US) | 2010-01-27 | — | — | EP | claimed |
| WO-2009020677-A9 | COMPOSITIONS AND METHODS FOR INHIBITING G PROTEIN SIGNALING | UNIV ROCHESTER (US) | 2009-04-16 | — | — | WO | claimed |
| WO-2009020677-A2 | COMPOSITIONS AND METHODS FOR INHIBITING G PROTEIN SIGNALING | UNIVERSITY OF ROCHESTER (US) | 2009-02-12 | — | — | WO | claimed |
| US-4191533-A | Pregnancy-specific β1 -glycoprotein and process for isolating it | BEHRINGWERKE AKTIENGESELLSCHAFT (DE) | 1980-03-04 | — | — | US | disclosed |
| US-4065445-A | Pregnancy-specific β1 -glycoprotein and process for isolating it | BEHRINGWERKE AKTIENGESELLSCHAFT (DT) | 1977-12-27 | — | — | US | disclosed |