Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | TYK2 | P29597 | 1/20 | 0.48 |
| ▸ | SNCA | P37840 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.47 |
| ▸ | AR | P10275 | 1/20 | 0.47 |
| ▸ | CBR1 | P16152 | 1/20 | 0.47 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.47 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.47 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27799819 | 0.87 | NPC1 (0.61) | MAPTKDM4EMEN1KMT2ANPC1 | |
| SCHEMBL21629913 | 0.86 | MEN1 (0.57) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL19052112 | 0.85 | HPGD (0.59) | KDM4EMEN1KMT2ANPC1RAB9A | |
| SCHEMBL27778782 | 0.84 | TYK2 (0.55) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL27778789 | 0.82 | NPC1 (0.51) | MAPTKDM4ENPC1RAB9ALMNA | |
| SCHEMBL20413311 | 0.78 | NPC1 (0.67) | MAPTKDM4EMEN1KMT2ANPC1 | |
| SCHEMBL2702708 | 0.78 | PLAU (0.66) | MAPTKDM4EMEN1KMT2ANPC1 | |
| SCHEMBL19799113 | 0.78 | TYK2 (0.51) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL7113169 | 0.78 | SNCA (0.54) | MEN1KMT2ANPC1RAB9ACYP1A2 | |
| SCHEMBL30739821 | 0.76 | JAK2 (0.69) | MAPTMEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101698651-A | Salicylanilide derivatives, preparation method thereof and application thereof | NANJING UNIVERSITY CHINA MEDIC | 2010-04-28 | — | — | CN | disclosed |