Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 6/20 | 0.53 |
| ▸ | LMNA | P02545 | 5/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL934859 | 0.80 | HTT (0.71) | HTTLMNAHSD17B10HPGDKDM4E | |
| SCHEMBL19052112 | 0.78 | HPGD (0.59) | HTTLMNAHSD17B10HPGDKDM4E | |
| SCHEMBL2699674 | 0.76 | LMNA (0.73) | HTTLMNAHSD17B10HPGDKDM4E | |
| SCHEMBL27803932 | 0.73 | KDR (0.69) | HTTLMNAHPGDKDM4EALDH1A1 | |
| SCHEMBL27799819 | 0.73 | NPC1 (0.61) | HTTLMNAHSD17B10KDM4ENPC1 | |
| SCHEMBL7223414 | 0.72 | HTT (0.52) | HTTLMNAHSD17B10HPGDKDM4E | |
| SCHEMBL23752320 | 0.72 | F2R (0.51) | HTTLMNAALDH1A1MAPK1KMT2A | |
| SCHEMBL6924667 | 0.72 | CXCR1 (0.73) | HTTLMNANPC1RAB9ATP53 | |
| SCHEMBL5594844 | 0.72 | CXCR1 (0.73) | HTTLMNANPC1RAB9ATP53 | |
| SCHEMBL31092076 | 0.71 | HPGD (0.68) | HTTLMNAHSD17B10HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101698651-A | Salicylanilide derivatives, preparation method thereof and application thereof | NANJING UNIVERSITY CHINA MEDIC | 2010-04-28 | — | — | CN | disclosed |