Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NNMT | P40261 | 4/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | GRM5 | P41594 | 1/20 | 0.44 |
| ▸ | F7 | P08709 | 1/20 | 0.42 |
| ▸ | F3 | P13726 | 1/20 | 0.42 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.42 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.42 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.42 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.42 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.42 |
| ▸ | SIRT4 | Q9Y6E7 | 1/20 | 0.42 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.42 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.42 |
| ▸ | HPGDS | O60760 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2937228 | 0.84 | NNMT (0.57) | NNMTSMN1; SMN2KDM4EL3MBTL1GRM5 | |
| SCHEMBL5234177 | 0.84 | NNMT (0.57) | NNMTSMN1; SMN2KDM4EL3MBTL1GRM5 | |
| SCHEMBL30557594 | 0.84 | NNMT (0.57) | NNMTSMN1; SMN2KDM4EL3MBTL1GRM5 | |
| SCHEMBL9786932 | 0.82 | NNMT (0.55) | NNMTSMN1; SMN2KDM4EL3MBTL1GRM5 | |
| SCHEMBL5175746 | 0.82 | NNMT (0.55) | NNMTSMN1; SMN2KDM4EL3MBTL1GRM5 | |
| SCHEMBL5293898 | 0.82 | NNMT (0.55) | NNMTSMN1; SMN2KDM4EL3MBTL1GRM5 | |
| SCHEMBL30826948 | 0.81 | NNMT (0.53) | NNMTSMN1; SMN2KDM4EL3MBTL1GRM5 | |
| SCHEMBL2935799 | 0.79 | NNMT (0.52) | NNMTSMN1; SMN2KDM4EL3MBTL1GRM5 | |
| SCHEMBL29537517 | 0.79 | NNMT (0.52) | NNMTSMN1; SMN2KDM4EL3MBTL1GRM5 | |
| SCHEMBL2691837 | 0.79 | NNMT (0.52) | NNMTSMN1; SMN2KDM4EL3MBTL1GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101687791-A | 5-lipoxygenase-activating protein (flap) inhibitors | AMIRA PHARMACEUTICALS INC | 2010-03-31 | — | — | CN | disclosed |