Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | MGAM | O43451 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ITK | Q08881 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1225412 | 0.87 | ALDH1A1 (0.58) | SLC6A4SMN1; SMN2LMNAL3MBTL1LPAR2 | |
| SCHEMBL10288441 | 0.83 | SLC6A4 (0.52) | SLC6A4SMN1; SMN2LMNAL3MBTL1MGAM | |
| SCHEMBL2135499 | 0.83 | SLC6A4 (0.52) | SLC6A4SMN1; SMN2LMNAL3MBTL1MGAM | |
| SCHEMBL2135495 | 0.83 | SLC6A4 (0.52) | SLC6A4SMN1; SMN2LMNAL3MBTL1MGAM | |
| SCHEMBL12881257 | 0.79 | SMN1; SMN2 (0.60) | SMN1; SMN2LMNAL3MBTL1KDM4ECYP1A2 | |
| SCHEMBL2136056 | 0.79 | SLC6A4 (0.51) | SLC6A4SMN1; SMN2LMNAMGAMKDM4E | |
| SCHEMBL15799376 | 0.79 | SLC6A4 (0.51) | SLC6A4SMN1; SMN2LMNAMGAMKDM4E | |
| SCHEMBL15805082 | 0.79 | SLC6A4 (0.51) | SLC6A4SMN1; SMN2LMNAMGAMKDM4E | |
| SCHEMBL2136050 | 0.79 | SLC6A4 (0.51) | SLC6A4SMN1; SMN2LMNAMGAMKDM4E | |
| SCHEMBL1223824 | 0.78 | SLC6A4 (0.53) | SLC6A4SMN1; SMN2MGAMKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010132615-A1 | HYDRAZONE COMPOUNDS AND THEIR USE | STEIN PHILIP (US) | 2010-11-18 | — | — | WO | disclosed |