Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 2/20 | 0.32 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.30 |
| ▸ | SELE | P16581 | 1/20 | 0.30 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1563996 | 0.83 | GAA (0.33) | PDE4DICAM1SELEVCAM1 | |
| Hydrochloric Acid SCHEMBL6627836 | 0.80 | GAA (0.32) | PDE4D | |
| SCHEMBL1564290 | 0.73 | NOX1 (0.30) | — | |
| Hydrochloric Acid SCHEMBL1564805 | 0.71 | — | — | |
| SCHEMBL4802054 | 0.70 | PDE4D (0.35) | PDE4DICAM1SELEVCAM1 | |
| Hydrochloric Acid SCHEMBL1563435 | 0.69 | PDE4D (0.33) | PDE4D | |
| SCHEMBL2874874 | 0.67 | PDE4D (0.38) | PDE4DICAM1SELEVCAM1 | |
| SCHEMBL2874872 | 0.67 | ADH1B (0.32) | — | |
| SCHEMBL2874875 | 0.67 | SLC6A4 (0.40) | — | |
| SCHEMBL1564966 | 0.66 | PDE4D (0.43) | PDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101679375-A | 8-oxy-quinoline derivatives as bradykinin b2 receptor modulators | JERINI AG | 2010-03-24 | — | — | CN | disclosed |